Predicting Infant Extubation Using Diaphragm Surface Electromyography
- Conditions
- Infant, Newborn, Disease
- Interventions
- Device: Recording of diaphragm EMG
- Registration Number
- NCT02878993
- Lead Sponsor
- King's College London
- Brief Summary
This study aims to assess whether the electrical signal of the diaphragm (diaphragm electromyogram) and the ratio of that to tidal volume (amount of air breathed in and out of the lungs) can predict which infants will be successfully extubated (have the breathing tube removed without needing it replaced.)
- Detailed Description
This study aims to assess whether the electrical signal of the diaphragm (diaphragm electromyogram) and the ratio of that to tidal volume (amount of air breathed in and out of the lungs) can predict which infants will be successfully extubated (have the breathing tube removed without needing it replaced.)
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 72
- intubated and mechanically ventilated on NICU
- major congenital abnormalities
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Intubated infants Recording of diaphragm EMG Recording of diaphragm EMG
- Primary Outcome Measures
Name Time Method Magnitude of diaphragm EMG One hour Magnitude of diaphragm EMG
Ratio of diaphragm EMG to tidal volume One hour Ratio of diaphragm EMG to tidal volume
- Secondary Outcome Measures
Name Time Method Extubation success 48 hours Extubation success is define as remaining free of invasive mechanical ventilation. Whether the above measures of diaphragm EMG can predict such success will be investigated
Trial Locations
- Locations (1)
King's College Hospital
🇬🇧London, United Kingdom