MedPath

Pancreatic Cyst Follow-up study

Conditions
Pancreatic cystsFollow-upPancreatic cystic neoplasms
Registration Number
NL-OMON27080
Lead Sponsor
Erasmus University Medical Center in Rotterdam, The Netherlands
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
5000
Inclusion Criteria

• Individuals with a pancreatic cyst (either newly or previously diagnosed)

• Cyst surveillance is warranted, according to the treating physician

Exclusion Criteria

• History of chronic pancreatitis

• Suspected pseudocyst

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Primary outcomes are: the number of patients that reach an indication for surgical cyst resection and the number of patients diagnosed with a malignant cyst (either high-grade dysplasia or carcinoma).
Secondary Outcome Measures
NameTimeMethod
Secondary outcomes are: <br /><br>1. the outcome of patients with an indication for cyst resection; i.e. the number of operated patients, surgical procedures, morbidity, mortality, and cyst recurrence <br /><br>2. cyst evolution, in terms of development of symptoms, cyst growth, nodules, and secondary pancreatic duct dilatation<br /><br>3. the perceived burden of surveillance on participants. <br /><br>4. possible risk factors for malignancy, either patient or cyst related<br /><br>5. to build a micro-simulation screening analysis (MISCAN) model, based on the outcome data of this study, in order to determine the optimal strategy for pancreatic cyst surveillance.
© Copyright 2025. All Rights Reserved by MedPath