Sit-to-stand Test Use in Children and Adolescents With Cystic Fibrosis : Correlations With 6-Minute Walking Test, Quadriceps and Respiratory Muscle Strength and Health Related Quality of Life
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 5
- 主要终点
- Correlation between number of repetitions (STS Test) and 6-Minute Walking Distance
研究概览
简要总结
Cystic fibrosis (CF) is a chronic hereditary respiratory disease. Exercise testing is part of CF patients regular assessment.
Cardio-Pulmonary Exercise Testing (CPET) is currently considered as the gold standard to assess physical capacities. However, simple field tests are emerging. These tests are easier to perform especially in a population of CF children and adolescents.
The 1minute Sit-To-Stand test have recently been evaluated in CF adults. This test correlates with maximal oxygen consumption during CPET.
The investigators hypothesized that this test also correlates with 6-Minute Walking distance (during a 6-min Walk Test), quadriceps strength, respiratory muscles strength and health-related quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cystic Fibrosis
- •Exacerbation-free last month before inclusion
排除标准
- •Cardiovascular, neurological or musculoskeletal contra-indications to exercise testing
- •Other respiratory disease (kyphoscoliosis, asthma ...)
- •Exacerbation
- •Unability to carry out field tests
结局指标
主要结局
Correlation between number of repetitions (STS Test) and 6-Minute Walking Distance
时间窗: This outcome will be measured after both tests realization up to 15 minutes.
Comparison between the results of these two submaximal exercise tests
次要结局
- Correlation between number of repetitions (STS test) and Maximal Inspiratory Pressure (MIP)(MIP will be measured after inclusion in the hour before field tests realization.)
- Correlation between number of repetitions (STS test) and Maximal Expiratory Pressure (MEP)(MEP will be measured after inclusion in the hour before field tests realization.)
- Correlation between number of repetitions (STS Test) and health-related quality of life(HRQoL testing will be carried out after inclusion in the hour before field tests realization.)
- Differences in dyspnea and muscular fatigue.(These outcomes will be assessed during both field tests. These tests will be separate by a 30 minutes rest period. Date will be collected at the end of each test up to 15 minutes.)
- Correlation between number of repetitions (STS Test) and forced vital capacity (FVC)(Spirometric test will be carried out before field tests realization.)
- Correlation between number of repetitions (STS Test) and number of exacerbations / year.(Number of exacerbations / year will assess the number of exacerbations in the last year before inclusion and will be assessed during the initial survey in the hour before field test realization.)
- Differences in Respiratory Rate.(These outcomes will be assessed during both field tests. These tests will be separate by a 30 minutes rest period. Date will be collected at the end of each test up to 15 minutes)
- Correlation between number of repetitions (STS Test) and quadriceps strength.(Quadriceps strength will be assessed after inclusion in the hour before field tests realization.)
- Correlation between number of repetitions (STS Test) and forced expiratory volume in 1 second (FEV1)(Spirometric test will be carried out in the last 3 months before field tests realization.)
- Differences in Heart Rate.(These outcomes will be assessed during both field tests. These tests will be separate by a 30 minutes rest period. Date will be collected at the end of each test up to 15 minutes.)
- Differences in Oxygen Saturation.(These outcomes will be assessed during both field tests. These tests will be separate by a 30 minutes rest period. Date will be collected at the end of each test up to 15 minutes.)