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Clinical Trials/NCT05435950
NCT05435950
Completed
Not Applicable

Prospective, Monocenter, Non-randomized Clinical Investigation Evaluating the Safety, Clinical Performance and Effectiveness of Sono-instruments for the Percutaneous Ultrasound-guided Treatment of Carpal Tunnel Syndrome and Trigger Finger

Spirecut1 site in 1 country30 target enrollmentSeptember 2, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Trigger Finger
Sponsor
Spirecut
Enrollment
30
Locations
1
Primary Endpoint
Safety of percutaneous surgery performed with Sono-Instuments
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Carpal Tunnel (CT) syndrome is a collection of characteristic symptoms and signs that occurs following compression of the median nerve within the CT. In Trigger Finger / trigger thumb (TF), one of the most common causes of hand pain and disability, the flexor tendon causes painful popping or snapping as the patient flexes and extends the digit. In case of failure of non-operative treatments, patients with CT syndrome or TF are operated. Clearly any improvement in surgical device design would be of great advantage to the patient and the surgeon. Spirecut's single use, pre-CE Sono-Instruments (SI) allow the percutaneous treatment of Carpal Tunnel (CT)syndrome and Trigger Finger/thumb (TF) under sonography (instead of open or endoscopic approach). Two models will be assessed in this clinical investigation:

  1. The Carpal Tunnel Sono-Instrument® (CT-SI), for CT syndrome release, by progressively cutting the transverse carpal ligament.
  2. The Trigger Finger Sono-Instrument® (TF-SI), for TF release by progressively cutting the A1 annual pulley.

Using those SI, surgical procedures can be performed without endangering adjacent structures (e.g. median nerve and branches, ulnar pedicle, superficial carpal arch, digital pedicles, flexor tendons).

Registry
clinicaltrials.gov
Start Date
September 2, 2022
End Date
March 10, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Spirecut
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adults ≥ 18 years of age;
  • Primary CT confirmed by typical symptoms, signs and altered nerve conduction studies;
  • Pain and/or numbness in the hand which worsen at night (or are present only at night);
  • Participant and investigator signed and dated the Informed Consent Form (ICF) prior to the index-procedure.
  • Participants with Trigger Finger/thumb:
  • Inclusion Criteria:
  • Adults ≥ 18 years of age;
  • Typical signs and symptoms of TF/thumb caused by friction or blockade of flexor tendon(s) in digital sheath, without flexion contracture over 30° of the proximal interphalangeal (or interphalangeal for the thumb) joint, confirmed by altered flexor tendon(s) gliding and/or increased thickness of A1 digital pulley under sonography (sonography can be done just before the operation, that is after signature of the ICF);
  • Participant and investigator signed and dated the ICF prior to the index-procedure.
  • Exclusion criteria:

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Safety of percutaneous surgery performed with Sono-Instuments

Time Frame: 6 weeks after the procedure

Number of peri- and post-operative (serious) adverse events, including operative and post-operative complications (e.g. infection), symptomatic recurrences and re-interventions.

Secondary Outcomes

  • Performance of Sono-Instruments during percutaneous surgery(During the index procedure)
  • Pre-operative pain(During screening)
  • Clinical effectiveness of percutaneous surgery performed with Sono-Instruments(6 weeks after the procedure)
  • Post-operative pain of percutaneous surgery performed with Sono-Instruments(6 weeks after the procedure)

Study Sites (1)

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