Diastolic Heart Failure Management by Nifedipine (DEMAND)
Not Applicable
- Conditions
- Diastolic Heart Failure
- Registration Number
- JPRN-UMIN000003856
- Lead Sponsor
- DEMAND Investigators
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
Not provided
Exclusion Criteria
1) Valvular heart diseases with significant regurgitation and/or stenosis 2) Hypertrophic cardiomyopathy, restrictive cardiomyopathy, arrythmogenic right ventricular cardiomyopathy, and active myocarditis 3) Constrictive pericarditis 4) Cardiogenic shock 5) Planned coronary artery bypass grafting or percutaneous coronary intervention within 3 months 6) History of acute coronary syndrome or stroke within 3 months 7) Pregnancy or breastfeeding 8) Hypersensitivity or contraindication to nifedipine 9) Inability to obtain informed consent 10) Any conditions not suitable for the participation in this trial judged by the investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Heart failure clinical composite response endpoint
- Secondary Outcome Measures
Name Time Method Death Cardiovascular death Hospital admission Hospital admission for cardiovascular disease Hospital admission for worsening heart failure Hospital admission for acute myocardial infarction, angina, coronary artery bypass grafting and percutaneous coronary intervention Stroke