Effect-site Concentration of Remifentanil for Smooth Removal of the LMA From Propofol Anesthesia
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 27
- 试验地点
- 1
- 主要终点
- smooth removal of LMA
研究概览
简要总结
The investigators attempted to determine the optimal effect-site concentration of remifentanil for smooth removal of the LMA from propofol anesthesia.
详细描述
At the end of the surgery, propofol infusion was stopped and remifentanil was titrated to predetermined (initial concentration 1.0 ng/ml for the first patient). LMA removal was performed when the patients opened their eyes and spontaneous respiration and adequate tidal volume and ventilatory frequency were confirmed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I-II patients undergoing general anesthesia for short elective surgery (<1 hr)
排除标准
- •G-E reflux
- •obesity (BMI>30)
- •anticipated difficult airway
研究组 & 干预措施
remifentanil
LMA removal was accomplished when remifentanil was maintained a predetermined concentration throughout the emergence periods.
干预措施: remifentanil (Drug)
remifentanil
LMA removal was accomplished when remifentanil was maintained a predetermined concentration throughout the emergence periods.
干预措施: laryngeal mask airway (LMA) (Device)
结局指标
主要结局
smooth removal of LMA
时间窗: from end of surgery to removal of LMA (participants will be followed for the emergence periods, an expected average of 15 min).
the response of patients to the removal of LMA (classified as either 'success \[smooth emergence\]' or 'failure') during infusion of remifentanil.
次要结局
未报告次要终点
研究者
Jong Yeop Kim
Associate professor
Ajou University School of Medicine