The effect of acupuncture on the microcirculation of the human optic nerve head and the retina
Phase 4
- Conditions
- H40.1Primary open-angle glaucoma
- Registration Number
- DRKS00014565
- Lead Sponsor
- Klinik und Poliklinik für AugenheilkundeTechnische Universität Carl Gustav Carus Dresden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
Patients with Primary open-angle glaucoma
Exclusion Criteria
Exclusion criteria in glaucoma patients were: topical therapy with dorzolamide, diabetes, age-related macular degeneration (ARMD) and other ocular diseases, previous intraocular surgeries and/or retinal laser photocoagulation, ocular injuries, or lens/corneal opacities and smokers. Patients with migraine, epilepsy, uncontrolled arterial hypertension and prior (<4 weeks) steroid therapy, as well as pregnant/breastfeeding women were excluded from the study.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method After mydriasis with tropicamid-1 % (Mydrum; 5mg/1ml; Chauvin Ankerpharm, Germany) patients were instructed to sit for 10 min to achieve stable hemodynamic conditions. Blood pressure was measured and blood flow measurements started with the Heidelberg Retina Flowmeter (HRF), followed by the Ocular Blood Flow system (OBF) and the Retinal Vessel Analyzer (RVA). Measurements were taken only in one eye of each patient. After completion of all measurements acupuncture was performed in the same sitting position. Ten minutes after acupuncture above mentioned blood flow measurements were repeated in the same manner with the same devices.
- Secondary Outcome Measures
Name Time Method