To Compare Intravenous and Oral Hydration of the Prevention for CIN in Elderly Patients Undergoing Intravenous CECT
Not Applicable
- Conditions
- CIN
- Registration Number
- NCT03872739
- Lead Sponsor
- Yu Danqing
- Brief Summary
To Compare Intravenous and Oral Hydration of the Prevention for Contrast-induced Nephropathy in Elderly Patients Undergoing Intravenous Contrast-enhanced Computed Tomography.
- Detailed Description
The prospective multicenter randomized controlled clinical research discusses the comparison of oral and intravenous hydration for prevention of contrast-induced nephropathy in elderly patients with enhanced computed tomography, establishing a simple hydration proposal.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 1368
Inclusion Criteria
- Age>21
- informed consent
- Undergoing Intravenous Contrast-enhanced Computed Tomography
Exclusion Criteria
- CT enhancement was not performed;
- Dialysis treatment of patients with end-stage renal failure or heart, kidney transplantation;
- Exposure to radioactive contrast medium within 48 hours prior to or within 72 hours of examination;
- Acute decompensated heart failure;
- Allergic to radioactive contrast agent;
- Be subjected to life - threatening trauma;
- Severe infection;
- Surgery was performed within 2 days of CT examination.
- Combined with multiple myeloma, urinary obstruction, aortic dissection
- Can cause acute kidney injury disease;
- Use of aminoglycosides and other nephrotoxic drugs 2 weeks before.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method CIN 72hours Compared with before examination, the increase of serum creatinine conforms to the diagnostic criteria of contrast induced nephropathy.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Guangdong provincial people's hospital
🇨🇳Guanzhou, Guangdong, China
Guangdong provincial people's hospital🇨🇳Guanzhou, Guangdong, Chinahuang jieleng, doctorContact