Dermogenesis With Mesenchymal Stem Cells: A Fabulous Remedy For Post Acne Depressed Spots
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Dermal thickness
Study Overview
Brief Summary
Dermogenesis With Mesenchymal Stem Cells in treating Post Acne Depressed Spots
Detailed Description
management at two different stages of the course of the disease. First one at the stage of active disease which needs cleansers, antibiotics, retinoids, anti inflammatory agents and hormonal manipulation. Once active disease is over, patients report to clinician with depressed spots which are caused by localized dermal disruption and fat atrophy post inflammation or spontaneous epithelial rupture or scratching by the patient. These acne spots are hard to treat due to many reasons. Firstly, excision is difficult as size of most of them is small and they are in a large in number. Secondly, filling with and without subcision is not adequately addressing the deformity. Currently, a combination of filling with synthetic filler or fat and resurfacing by peeling, LASER or dermabrasion is in practice. In-spite of all, a treatment is still required to address post acne spots (Ice Spec Spots) adequately.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- — to 50 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Acne spots
Exclusion Criteria
- •Active acne
Arms & Interventions
Mesenchymal stem cells
Mesenchymal Stem Cells taken from adipose tissue will be used
Intervention: Autologous Mesenchymal stem cells injection (Procedure)
Homogenized fat
Adipose tissue will be harvested and used
Intervention: Homogenized fat injection (Procedure)
Outcomes
Primary Outcomes
Dermal thickness
Time Frame: 3 months
on microscopy of biopsy section
Secondary Outcomes
No secondary outcomes reported
Investigators
Afzaal Bajwa
Assistant Professor
King Edward Medical University
