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Clinical Trials/NCT06135519
NCT06135519CompletedNot Applicable

Dermogenesis With Mesenchymal Stem Cells: A Fabulous Remedy For Post Acne Depressed Spots

King Edward Medical University1 site in 1 country20 target enrollmentStarted: July 23, 2023Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
20
Locations
1
Primary Endpoint
Dermal thickness

Study Overview

Brief Summary

Dermogenesis With Mesenchymal Stem Cells in treating Post Acne Depressed Spots

Detailed Description

management at two different stages of the course of the disease. First one at the stage of active disease which needs cleansers, antibiotics, retinoids, anti inflammatory agents and hormonal manipulation. Once active disease is over, patients report to clinician with depressed spots which are caused by localized dermal disruption and fat atrophy post inflammation or spontaneous epithelial rupture or scratching by the patient. These acne spots are hard to treat due to many reasons. Firstly, excision is difficult as size of most of them is small and they are in a large in number. Secondly, filling with and without subcision is not adequately addressing the deformity. Currently, a combination of filling with synthetic filler or fat and resurfacing by peeling, LASER or dermabrasion is in practice. In-spite of all, a treatment is still required to address post acne spots (Ice Spec Spots) adequately.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
— to 50 Years (Child, Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Acne spots

Exclusion Criteria

  • •Active acne

Arms & Interventions

Mesenchymal stem cells

Experimental

Mesenchymal Stem Cells taken from adipose tissue will be used

Intervention: Autologous Mesenchymal stem cells injection (Procedure)

Homogenized fat

Experimental

Adipose tissue will be harvested and used

Intervention: Homogenized fat injection (Procedure)

Outcomes

Primary Outcomes

Dermal thickness

Time Frame: 3 months

on microscopy of biopsy section

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Afzaal Bajwa

Assistant Professor

King Edward Medical University

Study Sites (1)

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