Dermogenesis With Mesenchymal Stem Cells
- Conditions
- Dermal Regeneration
- Interventions
- Procedure: Homogenized fat injectionProcedure: Autologous Mesenchymal stem cells injection
- Registration Number
- NCT06135519
- Lead Sponsor
- King Edward Medical University
- Brief Summary
Dermogenesis With Mesenchymal Stem Cells in treating Post Acne Depressed Spots
- Detailed Description
management at two different stages of the course of the disease. First one at the stage of active disease which needs cleansers, antibiotics, retinoids, anti inflammatory agents and hormonal manipulation. Once active disease is over, patients report to clinician with depressed spots which are caused by localized dermal disruption and fat atrophy post inflammation or spontaneous epithelial rupture or scratching by the patient. These acne spots are hard to treat due to many reasons. Firstly, excision is difficult as size of most of them is small and they are in a large in number. Secondly, filling with and without subcision is not adequately addressing the deformity. Currently, a combination of filling with synthetic filler or fat and resurfacing by peeling, LASER or dermabrasion is in practice. In-spite of all, a treatment is still required to address post acne spots (Ice Spec Spots) adequately.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
- Acne spots
- Active acne
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Homogenized fat Homogenized fat injection Adipose tissue will be harvested and used Mesenchymal stem cells Autologous Mesenchymal stem cells injection Mesenchymal Stem Cells taken from adipose tissue will be used
- Primary Outcome Measures
Name Time Method Dermal thickness 3 months on microscopy of biopsy section
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
King Edward Medical University
🇵🇰Lahore, Punjab, Pakistan