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临床试验/NCT02555488
NCT02555488Unknown2 期

Comparing the Antibacterial Effect of 810 nm Diode Laser and Photodynamic Therapy in Reducing the Microbial Flora of the Canal While Root Retreatment in Patients With Periradicular Lesions

Shahid Beheshti University1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2015年1月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
2 期
入组人数
20
试验地点
1
主要终点
bacterial colony forming unit(CFU/ML)

研究概览

简要总结

The aim of this study was to compare the Antibacterial Efficacy of Diode Laser 810nm and Photodynamic therapy in reducing bacterial microflora in endodontic retreatment of teeth with periradicular lesion.

详细描述

Conventional techniques of root canal treatments such as mechanical instrumentation and chemical debridement with antimicrobial irrigants, such as Sodium hypochlorite (NaOCl) and chlorhexidine and use of calcium hydroxide do not always suffice to predictably render root canals free of bacteria Using the high-power diode laser is a new approach of disinfection allowing access to the previously unavailable areas, such as the tubular network. This study, therefore, compares two types of diode lasers (low-power and high power) in terms of anti-bacterial effect as well as the conventional endodontic retreatment to determine the ideal method of root canal disinfection.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • endodontic retreatment of teeth with periradicular lesion.

排除标准

  • 未提供

研究组 & 干预措施

2

Experimental

in the second group diode laser (810 nm, 1.2 W, 30 s) was irradiated. Then second samples were taken from all canals.

干预措施: diode laser (Device)

1

Experimental

In the first group Photodynamic therapy (PDT) with Methylene blue and diode laser (810 nm, 0.2 W, 40 second) was done

干预措施: diode laser (Device)

1

Experimental

In the first group Photodynamic therapy (PDT) with Methylene blue and diode laser (810 nm, 0.2 W, 40 second) was done

干预措施: Methylene blue (Drug)

结局指标

主要结局

bacterial colony forming unit(CFU/ML)

时间窗: 12 months

after doing protocol in each groups CFU /ml for different bacteria will be counted

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

saranaz azari-marhabi

dr

Shahid Beheshti University

研究点 (1)

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