CTRI/2022/02/040276已完成未知
A study to evaluate the effect of Alpha lipoic acid on inhibition of platelet aggregation in diabetic neuropathy patients on Gabapentin or Pregabalin
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 52
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Type 2 diabetic patients of either sex aged between 30 - 65 years
- •2.Duration of diabetes >10 ± 5 years
- •3.Symptomatic diabetic polyneuropathy patients with VPT value more than 15V
- •4.HbA1c < 10%
- •5.Patients on stable dose of antidiabetic drug or combination of Metformin + sulphonyl urea +
- •DPP4 Inhibitors for the past 3 months
- •6.Patients on stable dose of Gabapentin 300 mg BD or Pregabalin 75mg BD for past 3 months
- •7.Serum creatinine < 2 mg/dl
排除标准
- •1.Any other conditions causing neuropathic pain
- •2.History of hypersensitivity to alpha Lipoic acid
- •3.Patients on antiplatelet drugs
- •4.Patients receiving other antioxidants
- •5.Patients with active cardiovascular disease
- •6.Patients with liver dysfunction (ALT / AST > 3 times the upper limit of normal)
- •7.Patients with clinically significant skin disease
- •8.Pregnant and lactating women.
研究者
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