Cis atracurium and Tourniquet

Not Applicable

• Conditions: Cis atracurium.

• Registration Number: IRCT20151107024909N11
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Operation is elective
Operation needs general anesthesia
Body mass index is between 18 -30
Age is between 20 - 60 years

Exclusion Criteria

History of liver disease
History of kidney disease
History of severe cardiopulmonary disease
History of known neuromuscular disease such as: Guillain- Barre syndrome, Myasthenia gravis, Organophosphate and Anticholinesterase intoxication, multiple sclerosis disease and history of any musculoskeletal weakness in limbs
Usage of drugs such as: Aminoglycosides, Polymyxin, Lincomycin, Clindamycin, Tetracycline, Calcium, Magnesium, Lithium, Verapamil, Amlodipine, Anti epileptic drugs, Furosemide, Dantrolene, Azathioprine, Steroid and Tamoxifen
History of any vascular disease such as: Venous and arterial emboli, any impairment in circulation of limbs, Hemodialysis and history of any surgery on vessels of limbs.
Sickle cell anemia
Acidosis
Infection in limbs
Fracture in limbs
Tumor in limbs
Any increase in intracranial pressure
Addicted patient
Surgery on limbs that were examined
If neuromuscular monitoring is necessary during operation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Onset time of complete neuromuscular blockage. Timepoint: From administration of Cis atracurium until complete neuromuscular blockage. Method of measurement: With Chronometer.;Complete neuromuscular block duration. Timepoint: The time between complete neuromuscular block until onset of recovery. Method of measurement: With Chronometer.;The time of neuromuscular block recovery. Timepoint: The time between onset of recovery until complete recovery of neuromuscular block. Method of measurement: With Chronometer.