Discontinuation for Oral Anticoagulants in Patients With Atrial Fibrillation

• Conditions: Auricular Fibrillation; Anticoagulant Drugs

• Registration Number: NCT04133545
• Lead Sponsor: Hospital Italiano de Buenos Aires

Brief Summary

The purpose of this study is to compare the discontinuation rates for vitamin K antagonists and for direct oral anticoagulants during their first year

Detailed Description

The purpose of this study is to compare the discontinuation rates for vitamin K antagonists and for direct oral anticoagulants during their first year of use after their initiation during hospitalization in patients covered by our health insurance plan.

Study Timeline

• Study Start: 2018-04-04
• Primary Completion: 2019-09-30
• Status Verified: 2019-10
• Study First Submitted: 2019-10-17
• Study First Submitted QC: 2019-10-17
• Last Update Submitted: 2019-10-17
• Study First Posted: 2019-10-21
• Last Update Posted: 2019-10-21
• Study Completion: 2020-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 360

Inclusion Criteria

1. Patient older than 18 years of age covered by our Health Care Insurance Plan.
2. Indication for oral anticoagulation with an expected duration of use of no less than 1 year.

Exclusion Criteria

1. Refusal to take part.
2. Use of oral anticoagulants within 6 months prior to admission.
3. Presence of mechanical prosthetic valve.
4. Chronic renal failure with creatinine clearance <30 mL/min (estimated using the MDRD formula).

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anticoagulant Discontinuation Rate	One year	Anticoagulant Discontinuation Rate

Secondary Outcome Measures

Name	Time	Method
Discontinuation Predictors	One year	Discontinuation Predictors

Trial Locations

Locations (1)

Hospital Italiano de Buenos Aires; 🇦🇷 Buenos Aires, Argentina