Evaluating the impact of a weight loss on the burden of Atrial fibrillation ( AF) in obese patients

Adelaide University0 个研究点目标入组 356 人开始时间: 2014年10月23日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•Age: 18 – 85 years
•paroxysmal or persistent AF
•Paroxysmal AF defined as recurrent episodes that self-terminate within 7 days or persistent AF as recurrent episodes that last more than 7 days and may be terminated with cardioversion.
•Stable or no coronary artery disease.
•Risk Factors identified at initial assessment including obesity (BMI>27), hypertension, diabetes, smoking and ETOH abuse.

•Significant cardiac valvulopathy
•Significant left ventricular systolic dysfunction (EF less than or equal than 45% on Simpson biplane estimation or regional wall motion abnormalities), obvious LV regional wall motion abnormality, dilated LV
•Myocardial infraction or cardiac surgery in the previous 12 months, and previous ablation for AF
•Right ventricular dysfunction with or without pulmonary hypertension (resting PASP equal to 45mmHg) and/or at least moderate tricuspid regurgitation
•Congenital heart disease
•Severe coronary heart disease.
•Uncontrolled endocrinopathy (adrenal, thyroid, etc.)
•Severe medical condition such as malignancies, autoimmune or inflammatory diseases, renal failure, or hepatic failure

发起方

Adelaide University