The flow of information during mental simulatio

Completed

• Conditions: epilepsy; 10042258

• Registration Number: NL-OMON37599
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

Patients aged at least 8 years with medically intractable epilepsy who undergo chronic invasive EEG monitoring as part of a presurgical evaluation for epilepsy surgery. Preoperative mental simulation test performance should be within normal limits.

Exclusion Criteria

Not being able to perform the test.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>In this study we measure both the behavioural responses (reaction-time and hand<br /><br>orientation distribution) as well as the electrophysiological signals from the<br /><br>ECoG electrodes. During the interference protocol, we investigate the influence<br /><br>of local cortical stimulation on task performance. All results will be<br /><br>presented as cortical maps showing the active areas and their interactions.<br /><br>This will provide a cortical network model for mental simulation. Finally, the<br /><br>effects of resection on the performance of the task will be used as a proof of<br /><br>the models predictive potential.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n.a.</p><br>