Safety and Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma

Phase 2

Completed

• Conditions: Open-angle Glaucoma
• Interventions: Drug: Anecortave Acetate Sterile Suspension, 30 mg/mL; Other: Anecortave Acetate Vehicle

• Registration Number: NCT00451152
• Lead Sponsor: Alcon Research

Brief Summary

The purpose of this study was to evaluate the safety and intraocular pressure (IOP)-lowering efficacy of anecortave acetate for treatment of elevated IOP in patients with open-angle glaucoma.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-03
• Study First Submitted: 2007-03-21
• Study First Submitted QC: 2007-03-21
• Study First Posted: 2007-03-23
• Primary Completion: 2009-07
• Study Completion: 2009-07
• Status Verified: 2012-05
• Disposition First Submitted: 2012-11-27
• Disposition First Submitted QC: 2012-11-27
• Last Update Submitted: 2012-11-27
• Disposition First Posted: 2012-11-28
• Last Update Posted: 2012-11-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 89

Inclusion Criteria

• Diagnosis of open-angle glaucoma;
• Other protocol-defined inclusion criteria may apply.

Exclusion Criteria

• Pseudoexfoliation;
• Pigment dispersion component;
• Other protocol-defined exclusion criteria may apply.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Anecortave Acetate Depot	Anecortave Acetate Sterile Suspension, 30 mg/mL	-
Anecortave Acetate Vehicle	Anecortave Acetate Vehicle	-

Primary Outcome Measures

Name	Time	Method
Mean Intraocular Pressure (IOP)	3 months

Secondary Outcome Measures

Name	Time	Method
Percent Treatment Failures	3 months

Trial Locations

Locations (1)

Texas; 🇺🇸 San Antonio, Texas, United States