A Clinical study on Tamra Sindura in the management of Psoriasis

Phase 3

Conditions: Health Condition 1: L99- Other disorders of skin and subcutaneous tissue in diseases classified elsewhereHealth Condition 2: L988- Other specified disorders of the skin and subcutaneous tissue

Registration Number: CTRI/2024/06/069506

Lead Sponsor: Dr B Bhaskara Rao

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1.Known cases of Psoriasis, without psoriatic arthropathy Exhibiting psoriatic triad – Bright pink or red lesions with pronounced edges, covered with silvery white scales, the scales can be easily separated from the lesion Under the scales there appears a pinkish moist tender skin With the scarping of the moist skin there appear tiny blood droplets (Auspitz’s sign)

2.Patients suffering from mild to moderate Psoriasis with less than 50 % of the body surface involvement

3.Patients having less than 10 years duration

4.Positive histo - pathological finding.(Skin-biopsy - optional)

Exclusion Criteria

1.Age below 18 years and above 60 years

2.Patients with other forms of Psoriasis like Guttate/ Pustular/ Erythrodermic/ inverse.

3.Patients suffering from severe Psoriasis with more than 50% of the body surface involvement

4.Patients having chronic disease i.e. more than10 years duration

5.Patients who cannot report in person every 2 weeks in the OPD

6.Patients with poorly controlled Hypertension ( >160/100 mmHg)

7.Patients with poorly controlled Diabetes Mellitus having Hb A1C of > 7.5%

8.Patients on medication with corticosteroids, phototherapy, biologics, antidepressants any other drugs that may have an influence on the outcome of the study.

9.Patients who have a past history of Atrial Fibrillation, Acute Coronary Syndrome, Myocardial Infarction, Stroke or Severe Arrhythmia in the last 6 months.

10.Symptomatic patient with clinical evidence of Heart failure.

11.Known HIV positive cases