Temporal Relationship in Recovery of Muscular Pain and Functional Variables in an Experimental Muscular Pain Model in Hamstrings

Completed

• Conditions: Pain, Muscle

• Registration Number: NCT03942562
• Lead Sponsor: Universidad San Jorge

Brief Summary

Basal measurements are taken in relation to the study variables. Immediately subjects perform eccentric exercise on right hamstrings to develop delayed onset muscle soreness (DOMS).

Measurements of the study variables are taken in the same conditions 48, 96 and 168 hours after the exercise to study the evolution of the variables while recovering from DOMS.

Detailed Description

Basal measurements are taken in relation to the study variables.

The variables are:

* pressure pain thresholds

* electromyography values

* static and dynamic plantar pressure measurement

* active knee extensibility

* maximal strength of knee flexors

* thermography

* scales of pain perception

Immediately subjects perform eccentric exercise on right hamstrings to develop DOMS (delay onset muscle soreness).

Measurements of the study variables are taken in the same conditions 48, 96 and 168 hours after the exercise to study the evolution of the variables while recovering from DOMS.

Study Timeline

• Study Start: 2018-10-15
• Study First Submitted: 2019-05-06
• Study First Submitted QC: 2019-05-07
• Study First Posted: 2019-05-08
• Primary Completion: 2019-08-31
• Study Completion: 2019-08-31
• Status Verified: 2020-11
• Last Update Submitted: 2020-11-09
• Last Update Posted: 2020-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 24

Inclusion Criteria

• not sedentary subject (IPAQ scale > 600 MET)
• healthy subjects, without pain nor injury at the moment

Exclusion Criteria

• subjects with acute or chronic pain on every spot of pelvis or lower limbs at the momento or for the last 3 months;
• subjects with history of severe injury in the hamstrings muscles;
• presence of serious illness;
• presence of pathologies in relation to chronic pain (as fibromyalgia, migraine disorders, non specific and chronic lumbar pain);
• not commitment for continuity in the study program;

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in spatio temporal parameters of gait	Baseline, 48 hours, 96 hours, 1 week	Changes in spatio temporal parameters of gait over a treadmill will be measurement using an optical measurement system consisting of a transmitting and receiving bar (OptoGait System).

Secondary Outcome Measures

Name	Time	Method
Changes in Pressure Pain Thresholds	Baseline, 48 hours, 96 hours, 1 week	Changes in pressure pain thresholds (PPT) will be determined with pressure algometry bilaterally over the leg and shoulder. PPT is defined as the exact time point where the pressure is first being perceived at painful.
Changes in knee-flexors maximal isometric muscle strength	Baseline, 48 hours, 96 hours, 1 week	Changes in knee-flexors maximal isometric strength (Newton) will be assessed by using a hand-held dynamometer.
Changes in subjective perception of pain and impairment: Two questionnaire (Modified 7-item Likert Scales)	48 hours, 96 hours, 1 week	Two questionnaires (Modified 7-item Likert Scales) are filled up by the subject to show subjective perception of pain related to movement along the recovery period.; Scale of pain intensity, from 0 (no pain) to 6 (higher pain intensity). Scale of functional impairment, from 0 (no impairment) to 6 (higher impairment).
Changes in active knee extension test	Baseline, 48 hours, 96 hours, 1 week	Changes in range of motion (°; degrees) will be assessed in both sides using the active knee extension (AKE) test.; AKE test: subject is lying prone with hip and knee flexed at 90°. Then, maximal knee extension is performed.
Electromyography (EMG) measurement during the tests	Baseline, 48 hours, 96 hours, 1 week	Electromyography values will be taken from hamstrings during the performance of gait analysis and dynamometry
Changes in thermography on hamstrings areas	Baseline, 48 hours, 96 hours, 1 week	A thermography image will be taken every day of assessment. Changes in colour pixels will be analysed to determine temperature changes.
Changes in static and dynamic plantar pressure measurement	Baseline, 48 hours, 96 hours, 1 week	Changes in static and dynamic plantar pressure measurement will be performed in every session by using a pressure platform.

Trial Locations

Locations (1)

Universidad San Jorge; 🇪🇸 Villanueva De Gállego, Zaragoza, Spain