NCT00780429Unknown不适用
Evaluation of Pharmacokinetic and Pharmacodynamic Parameters in Renal Transplant Patients Receiving Mycophenolic Acid and Stable for at Least 3 Months
Fondazione IRCCS Policlinico San Matteo di Pavia1 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2006年6月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 54
- 试验地点
- 1
研究概览
简要总结
Study of the pharmacokinetic and pharmacodynamic variability of mycophenolate mofetil in renal transplant patients already on long-term MMF treatment (at least 6 months post-transplant; at least 3 months in therapy).
Study hypothesis: to investigate whether long-term MMF therapy alters IMPDH biological activity and if there are any correlations with the risk of AR.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Renal transplant recipients
- •Age range: 18-70
- •Patients taking MMF
- •Able to understand and sign an informed consent
排除标准
- •Active myelodepression
- •Systemic infections or other that may affect MMF absorption
- •Pregnancy/breastfeeding
- •(History of) cancer
- •Drug abuse, psychiatric conditions
- •Already enrolled in other clinical trials or participation ended less than one month earlier
- •Known sensitivity to polysorbate 80 or MMF
研究者
研究点 (1)
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