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临床试验/NCT07330427
NCT07330427招募中不适用

Impact of Health Education on Knowledge, Attitude and Practice of Post-exposure Prophylaxis Among Health Care Workers at Aswan University Hospital, Egypt

Aswan University1 个研究点 分布在 1 个国家目标入组 340 人开始时间: 2025年6月1日最近更新:
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
340
试验地点
1
主要终点
Health Practice Change

研究概览

简要总结

Occupational exposure to blood-borne pathogens, such as human immune-deficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) for healthcare workers through contact with human blood and body fluids has become a major health concern as it poses a risk of transmission of these infectious agents.

According to the World Health Organization (WHO) report, about three million HCWs are exposed to blood-borne pathogens each year, of which 170,000 are exposed to HIV infections, 2 million to HBV infections, and 0.9 million to HCV infections. Most of the time, healthcare providers get exposure through the splash of blood or other body fluids into the eyes, nose, or mouth or nonintact skin exposure, and percutaneous injury occurs as a result of a break in the skin caused by a needlestick or sharps contaminated with blood or body fluids

详细描述

Post exposure prophylaxis is defined by the World Health Organization (WHO) as the medical intervention offered to prevent the transmission of blood-borne diseases following a potential exposure to HIV, HBV, HCV, and other viruses.

In developing regions, 40%-65% of HBV and HCV infections in health care workers are attributable to percutaneous occupational exposure .Approximately 3 out of 35 million HCWs worldwide experience needlestick injuries (NSIs) annually, exposing them to blood-borne pathogens .

In Egypt, like many developing countries, few efforts have been undertaken to raise awareness about needlestick injury (NSI) among HCWs . There is a lack of regulations and policies to protect HCWs from exposure. HCWs rarely receive training in infection control and standard precautions, even though these are low-cost solutions to reducing the risk of sharp injuries and have a high likelihood of being adopted .

There is a lack of data and surveillance concerning health care-related occupational exposures and the use of PEP. Furthermore, unsafe practices are frequently observed, placing patients and healthcare workers at risk of infection.

knowledge and practice of PEP for HIV/HBV. As a result, the study recommended the establishment of PEP training centre with proper guidelines in order to enhance the utilization of PEP.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
19 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • HCWs at the selected departments (physicians, nurses and housekeepers).
  • Age >18 years old and below 60 years old in both Genders.
  • HCWs which have direct contact with blood and body fluids.

排除标准

  • Age<18 years old and above 60 years old.
  • Non-medical staff at Aswan university hospital.
  • Health care workers which have no contact with blood or body fluids.

研究组 & 干预措施

Health Care workers

Experimental

About 340 participants of heath care workers undergoing assessment of knowledge, attitude and practice about post-exposure prophylaxis among health care workers at Aswan university hospital, Egypt Then they will undergo lecturers about about post-exposure prophylaxis, then reassessment will be done after 3 months

干预措施: Health Education (Procedure)

结局指标

主要结局

Health Practice Change

时间窗: 3 Months

Assessment of participants after taking health education lecturers about post-exposure prophylaxis regrading to knowledge, attitude and practice and this done by questionnaire as :The questionnaire consisted of three sections assessing knowledge, attitude, and practice regarding post-exposure prophylaxis (PEP). Section B assessed knowledge using nine close-ended questions, with adequate knowledge defined as ≥75% correct answers. Section C included seven items evaluating attitudes toward the importance and effectiveness of PEP, with scores ≥75% indicating a good attitude. Section D assessed PEP practices through nine questions, and good practice was defined as positive responses to more than 75% of items.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Fatma Ali Mahmoud Hussein

Demonstrator at Public Health and Community Medicine, Faculty of medicine

Aswan University

研究点 (1)

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