The association of ectopic fat and cardiovascular disease in people living with HIV and general populations: a cross-sectional analysis

niversity of Liverpool0 个研究点目标入组 100 人开始时间: 2024年2月16日最近更新: 2024年2月27日

试验速览

暂无简介。

•1. >40 years old
•2. HIV-positive
•3. Stable ART for >6 months with two VL <40 copies/ml based on local testing protocols
•4. CD4 count >200cells/mm3 for >2 years from recruitment
•5. Understand the study procedures, be able to comply with study procedures and voluntarily agree to participate by giving informed written consent

•1. Subjects unable to comply with the study protocol
•2. History of severe renal impairment (eGFR <30ml/min)
•3. History of severe hepatic impairment (Child-Pugh Score >9)
•4. Active hepatitis B or hepatitis C
•5. Any active illness, which in the opinion of the investigator precludes participation in the study
•6. History of cancer
•7. Active illicit intravenous drug use
•8. Investigators may decide the subject cannot proceed if there are any relevant other abnormal results in screening assessments
•9. History or current GLP-1 agonist use
•10. For female subjects: pregnancy or breastfeeding at screening.
•11. Subjects currently taking: Atypical antipsychotics, omega 3 supplements, Telmisartan/Irbesartan, Thiazolidinediones or regular NSAID use
•12. Familial hypercholesterolaemia

发起方

niversity of Liverpool