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Clinical Trials/NCT07413770
NCT07413770
Recruiting
Not Applicable

Effects of Classical Massage in Individuals With Myofascial Pain Syndrome: A Randomized Controlled Trial

Biruni University1 site in 1 country60 target enrollmentStarted: January 12, 2026Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Sponsor
Biruni University
Enrollment
60
Locations
1
Primary Endpoint
Pain Intensity

Overview

Brief Summary

The aim of this study is to evaluate the effects of classical massage on pain, muscle sensitivity, muscle activity, functional status, and quality of life in individuals with myofascial pain syndrome, and to compare the effectiveness of classical massage applied alone versus in combination with a conventional physiotherapy program.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
30 Years to 50 Years (Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Diagnosis of myofascial pain syndrome confirmed by a physical medicine and rehabilitation physician, according to the criteria of Travell and Simons (1992)
  • Male or female participants aged 30-50 years
  • Presence of at least one active trigger point in the upper trapezius muscle confirmed by palpation
  • Pain radiating to the neck and upper extremity persisting for at least 3 months
  • Pain intensity of ≥4/10 on the Visual Analog Scale (VAS)
  • Functional impairment indicated by a Neck Disability Index (NDI) score ≥10/50 (≥20%)
  • Written informed consent

Exclusion Criteria

  • Presence of diagnosed systemic musculoskeletal or rheumatologic disorders (e.g., fibromyalgia, rheumatoid arthritis)
  • Signs or symptoms of neuropathic pain or cervical radiculopathy
  • Conditions contraindicating massage therapy (e.g., skin infection, open wounds, bleeding disorders, active inflammation)
  • Receipt of manual therapy, massage, dry needling, injections, or similar treatments targeting the affected region within the preceding 1 month
  • Pregnancy or breastfeeding
  • History of acute trauma, fracture, or surgical intervention involving the neck or shoulder region

Arms & Interventions

Conventional Physiotherapy

Experimental

Intervention: Conventional treatment (Other)

Therapeutic massage

Experimental

Intervention: Therapeutic Massage (Other)

Combined treatment

Experimental

Intervention: combined treatment (Other)

Outcomes

Primary Outcomes

Pain Intensity

Time Frame: 6 weeks

The primary outcome of this study is pain intensity, will be assessed using the Visual Analog Scale (VAS), a 10-cm scale ranging from 0 (no pain) to 10 (worst imaginable pain), with higher scores indicating greater pain intensity.

Secondary Outcomes

  • Pressure Pain Threshold-Algometer(6 weeks)
  • Muscle Activity(6 weeks)
  • Functional Status (Neck Disability Index)(6 weeks)
  • Quality of Life (SF-12)(6 weeks)

Investigators

Sponsor
Biruni University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Begum Kara Kaya

Assistant Professor

Biruni University

Study Sites (1)

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