Effects of Short-term Sugary Beverage Consumption on Type-2 Diabetes and Cardiovascular Disease Risk Factors: A Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Metabolic Syndrome
- Sponsor
- Kansas State University
- Enrollment
- 37
- Locations
- 1
- Primary Endpoint
- Change in glucose iAUC
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Our goal is to determine how the addition of sugar-sweetened beverages to the diet affects glucose control, cardiovascular disease risk factors, and pulmonary function in healthy, young adults.
Detailed Description
In a 3-arm randomized controlled trial, 36 participants consumed one of three beverages for three weeks: water (W), caffeine-free soda (S), or 100% fruit juice (FJ). Participants consumed two servings/day (\~710mL) of their randomized beverage for three weeks, along with their habitual diets. At baseline and following the 3-week intervention, participants completed glucose control, cardiovascular disease risk factor, and pulmonary function assessments.
Investigators
Sara K Rosenkranz
Principal Investigator
Kansas State University
Eligibility Criteria
Inclusion Criteria
- •Free from diagnosis of diabetes and pulmonary illness
- •Have no intake of glucose or lipid lowering medication.
Exclusion Criteria
- •Currently pregnant
- •Have bronchitis
- •Have more than 2 risk factors for cardiovascular disease, as defined by the American College of Sports Medicine (ACSM).
Outcomes
Primary Outcomes
Change in glucose iAUC
Time Frame: Week 0 and Week 3
Glucose obtained from blood sample in a fasted state and in response to a meal
Secondary Outcomes
- Change in plasma lipids(Week 0 and Week 3)
- Change in blood pressure(Week 0 and Week 3)
- Change in serum fructosamine(Week 0 and Week 3)
- Change in insulin iAUC(Week 0 and Week 3)
- Change in homeostatic model assessment for insulin resistance(Week 0 and Week 3)
- Change in BMI(Week 0 and Week 3)
- Change in pulmonary function(Week 0 and Week 3)