Effects of Short-term Sugary Beverage Consumption on Type-2 Diabetes and Cardiovascular Disease Risk Factors: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 37
- 试验地点
- 2
- 主要终点
- Change in glucose iAUC
研究概览
简要总结
Our goal is to determine how the addition of sugar-sweetened beverages to the diet affects glucose control, cardiovascular disease risk factors, and pulmonary function in healthy, young adults.
详细描述
In a 3-arm randomized controlled trial, 36 participants consumed one of three beverages for three weeks: water (W), caffeine-free soda (S), or 100% fruit juice (FJ). Participants consumed two servings/day (~710mL) of their randomized beverage for three weeks, along with their habitual diets. At baseline and following the 3-week intervention, participants completed glucose control, cardiovascular disease risk factor, and pulmonary function assessments.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Free from diagnosis of diabetes and pulmonary illness
- •Have no intake of glucose or lipid lowering medication.
排除标准
- •Currently pregnant
- •Have bronchitis
- •Have more than 2 risk factors for cardiovascular disease, as defined by the American College of Sports Medicine (ACSM).
研究组 & 干预措施
Fruit Juice
Participants consumed 2 bottles of 100% fruit juice daily for 3 weeks.
干预措施: Sugary beverage: Fruit juice (Dietary Supplement)
Water
Participants consumed 2 bottles of water daily for 3 weeks.
干预措施: Control: Water (Dietary Supplement)
Soda
Participants consumed 2 cans of caffeine-free Coca Cola daily for 3 weeks.
干预措施: Sugary beverage: Soda (Dietary Supplement)
结局指标
主要结局
Change in glucose iAUC
时间窗: Week 0 and Week 3
Glucose obtained from blood sample in a fasted state and in response to a meal
次要结局
- Change in plasma lipids(Week 0 and Week 3)
- Change in blood pressure(Week 0 and Week 3)
- Change in serum fructosamine(Week 0 and Week 3)
- Change in insulin iAUC(Week 0 and Week 3)
- Change in homeostatic model assessment for insulin resistance(Week 0 and Week 3)
- Change in BMI(Week 0 and Week 3)
- Change in pulmonary function(Week 0 and Week 3)
研究者
Sara K Rosenkranz
Principal Investigator
Kansas State University