Whole blood thrombin generation test- a clinical validatio
- Conditions
- non-cardiac surgery (niet cardiale chirurgie), bleeding (bloeding), haemostasis (haemostase)
- Registration Number
- NL-OMON25031
- Lead Sponsor
- Maastricht University Medical Center andSynapse b.v. (CARIM)Oxfordlaan 706229EV Maastricht
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients undergoing major surgery (major abdominal surgery, aorta aneurysms, major orthopaedic surgery) that have a greater chance to develop a bleeding will be asked to participate to our study. Patient inclusion will only occur when they are suffering from a bleeding during/after major surgery receiving a transfusion of blood products and/or factor concentrates.
Exclusion Criteria
age below 18 years.
Patients with acute life-threatening bleeding.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Whole blood measeurement before and after treatment compared to standard plasma thrombin generation
- Secondary Outcome Measures
Name Time Method parameters of clinical bleeding (transfusion after the second test, fluid substitution)