Clinical profile of children who received high frequency ventilation for hypoxemic respiratory failure in post- OSCAR and OSCILLATE trials era
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- To compare the clinical profile of children with hypoxemic respiratory failure who survived on high frequency ventilation with children with hypoxemic respiratory failure who died on high frequency ventilation
研究概览
简要总结
THIS IS A SINGLE CENTRE, OBSERVATIONAL, STUDY WITH RETROSPECTIVE STUDY PERIOD OF 3 TEAR DURATION ( SINCE JANUARY 2017) AND PROSPECTIVE STUDY OF 1 YEAR PERIOD WHICH AIMS TO STUDY THE CLINICAL PROFILES OF CHILDREN BETWEEN AGES 1 MONTH AND 18 YEARS WITH HYPOXEMIC RESPIRATORY FAILURE WHO RECEIVED HIGH-FREQUENCY VENTILATION WITH SECONDARY OBJECTIVES OF STUDYING THE ASSOCIATION OF HFOV SETTINGS ON MORTALITY, VENTILATION DAYS, PICU STAY, AIR LEAKS, HEMODYNAMIC INSTABILITY, TO INVESTIGATE POSSIBLE OUTCOME PREDICTORS FOR CHILDREN ON HFOV, TO STUDY ASSOCIATION OF CUMULATIVE FLUID BALANCE, RENAL ANGINAL INDEX, AND PRONING MANEUVERS ON THE OUTCOME OF CHILDREN ON HFOV. RETROSPECTIVE DATA OF LAST 3 YEARS (SINCE JANUARY 2017 WILL ALSO BE COLLECTED)
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Month(s) 至 18.00 Year(s)（—）
- 性别
- All
入选标准
- •All children aged between 1 month and 18 years with hypoxemic respiratory failure requiring high frequency oscillation ventilation.
排除标准
- 未提供
结局指标
主要结局
To compare the clinical profile of children with hypoxemic respiratory failure who survived on high frequency ventilation with children with hypoxemic respiratory failure who died on high frequency ventilation
时间窗: 1 year
次要结局
- association of cumulative fluid balance, renal angina index on outcome of children on HFOV(1 year)
- association of HFOV settings on outcome parameters like ventilator days, air leaks, hemodynamic instability, PICU stay, mortality(1 year)
- association of proning maneuvers on the outcome of children on HFOV(1 year)
- possible outcome predictors for children with hypoxemic respiratory failure on HFOV(1 year)