Mapping the Lymphatic Drainage Pattern of Esophageal Cancer with Near-Infrared Fluorescent Imaging
Not Applicable
Recruiting
- Conditions
- C15.5Lower third of oesophagus
- Registration Number
- DRKS00016367
- Lead Sponsor
- Klinik und Poliklinik für Allgemein-, Viszeral- und TumorchirurgieUniklinik Köln
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Patients with clinically advanced stage adenocarcinoma of the esophagus (T2-T4, N0-N3) undergoing surgical resection
Exclusion Criteria
Patient refuses intervention
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patients will undergo laparoscopic mobilization of the stomach and abdominal lymphadenectomy, followed by transthoracic thoracoscopic or open esophagectomy and thoracic lymphadenectomy using fluorescence imaging as a guide for complete<br>lymph node dissection and to preserve the lymphatic channels. Affected nodes as detected by fluorescence imaging will be marked and dissected separately for later histopathological workup. Primary endpoint will be therefore the visualization of lymphatic channels along first and second tier nodes during the surgery.
- Secondary Outcome Measures
Name Time Method Pattern of lymph nodes metastatic spread of advanced esophageal Cancer along lymphatic channels (proximal to distal from the Tumor or has direct communication with distal nodes or multidirectional resulting skip metastasis). Visualization during surgery.