Effects of Aerobic Exercise Detraining

Completed

• Conditions: Body Weight; Obesity; Motor Activity

• Registration Number: NCT02158130
• Lead Sponsor: Pennington Biomedical Research Center

Brief Summary

The proposed study seeks to better understand the role of body weight, energy expenditure, and energy intake as mechanisms of body weight gain during detraining following aerobic exercise. It is hypothesized that participants in the higher dose exercise group will have greater body weight gain compared to the lower exercise dose and control group from wk 24 to wk 76 follow-up.

Detailed Description

Eligibility criteria include having successfully completed the main E-Mechanic study, be willing to archive blood samples and not being currently enrolled in another study that may effect body, energy intake or energy expenditure. The investigators will measure body weight, waist/hip circumference, blood pressure, body composition, physical activity, questionnaire about appetite/food intake and physical fitness.

Study Timeline

• Study First Submitted: 2014-06-04
• Study First Submitted QC: 2014-06-05
• Study First Posted: 2014-06-06
• Study Start: 2014-09
• Status Verified: 2016-03
• Primary Completion: 2016-03
• Study Completion: 2016-03
• Last Update Submitted: 2016-03-21
• Last Update Posted: 2016-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Completed the E-Mechanic study
• Be willing to archive blood samples
• Not participating in a study that would alter body weight, energy intake, or energy expenditure.

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Body Weight	Week 64 - 88 post study randomization	Fasting body weight

Secondary Outcome Measures

Name	Time	Method
Energy Expenditure	Week 64 - 90 since study randomization	Energy expenditure is calculated with the Sensewear Armband.
Energy Intake	Week 64 - 90 post study randomization	Energy expenditure is calculated with the Sensewear Armband and furthermore, energy intake is calculated by adjusting TDEE for change in body weight following the methods used in doubly labeled water adjustment.

Trial Locations

Locations (1)

Pennington Biomedical Research Center; 🇺🇸 Baton Rouge, Louisiana, United States