Effect of a Structured Clinical and Pharmacological Management Strategy on Cardiovascular Risk Factors in Adult Patients in Routine Clinical Practice: A Pseudo-Experimental Before-and-After Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 220
- 试验地点
- 1
- 主要终点
- Change in systolic blood pressure
研究概览
简要总结
This study aims to evaluate cardiovascular risk factors, clinical characteristics, and outcomes in adult patients attending an outpatient cardiology clinic. The research focuses on identifying predictors of adverse cardiovascular events, optimizing risk stratification, and improving preventive strategies in routine clinical practice. Data will be collected from patients receiving standard cardiology care without altering their treatment. The results are expected to contribute to better understanding of cardiovascular risk profiles and to support improvements in clinical decision-making and patient management.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥18 years
- •Presence of at least one cardiovascular risk factor (hypertension, diabetes, dyslipidemia, obesity, or smoking)
- •Receiving outpatient clinical follow-up
- •Ability to provide informed consent
排除标准
- •Severe clinical instability requiring hospitalization
- •Pregnancy
- •End-stage renal disease or dialysis
- •Inability to complete follow-up visits
- •Refusal to participate
研究组 & 干预措施
Structured Clinical Management
Participants receive structured clinical follow-up with periodic assessment of cardiovascular risk factors and adjustment of pharmacological and lifestyle management according to current clinical guidelines over a 120-day follow-up period.
干预措施: Structured Cardiovascular Risk Management (Other)
结局指标
主要结局
Change in systolic blood pressure
时间窗: Baseline to 90 days
Change in systolic blood pressure (mmHg) measured under standardized conditions to evaluate the effect of structured clinical and pharmacological cardiovascular risk management.
次要结局
- Change in diastolic blood pressure(Baseline to 90 days)
- Change in LDL cholesterol(Baseline to 90 days)
- Change in HbA1c(Baseline to 90 days)
- Change in body weight(Baseline to 90 days)
- Change in renal function (eGFR)(Baseline to 90 days)
- Change in HDL cholesterol(Baseline to 90 days)
- Change in triglycerides(Baseline to 90 days)
- Change in total cholesterol(Baseline to 90 days)
- Change in fasting plasma glucose(Baseline to 90 days)
- Change in body mass index(Baseline to 90 days)
- Change in microalbuminuria(Baseline to 90 days)
研究者
Julio Núñez Farías
Cardiologist and Principal Investigator
Universidad Católica San Antonio de Murcia