Multimodal Noninvasive Assessment of Peripheral Circulation in Chronic Limb-threatening Ischemia
- Conditions
- Chronic Limb Threatening Ischemia
- Registration Number
- NCT05786001
- Lead Sponsor
- Tampere University
- Brief Summary
Assessment of a novel diagnostic method for screening and diagnosing chronic limb-threatening ischemia (CLTI). Using hyperspectral and thermal imaging, the perfusion and oxygenation in the lower limbs will be studied in healthy and unhealthy individuals.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 150
- for CLTI patients age >50
- for age control group age >50 and not diagnosed with cardiovascular diseases. 0.9 < ABI < 1.3
- for healthy group 18 <= age <= 50 and no history of cardiovascular disease
- volunteering for study
- inability to give informed consent
- denial
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Perfusion in lower limb angiosomes assessed by thermal imaging 45 minutes during the procedure starting from the first measurement and ending after the last measurement Thermal imaging will be used to assess the perfusion in the lower limbs. The lower limb can be divided into six angiosomes, which can then be used to assess thermal patterns. Healthy and unhealthy feet will present with different thermal patterns and other changes in thermographs.
Oxygenation in lower limb angiosomes assessed by hyperspectral imaging. 45 minutes during the procedure starting from the first measurement and ending after the last measurement Hyperspectral imaging can be used in the assessment of oxygenation in the lower limb angiosomes. Based on hyperspectral imaging, oxygenation maps can be generated and then analyzed. Differences between the oxygenation maps of healthy and unhealthy patients will be established.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Tampere University
🇫🇮Tampere, Pirkanmaa, Finland