Evaluation of Lower Limb Angiosome Perfusion and Oxygenation Using Thermal and Hyperspectral Imaging
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Chronic Limb Threatening Ischemia
- Sponsor
- Tampere University
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- Perfusion in lower limb angiosomes assessed by thermal imaging
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
Assessment of a novel diagnostic method for screening and diagnosing chronic limb-threatening ischemia (CLTI). Using hyperspectral and thermal imaging, the perfusion and oxygenation in the lower limbs will be studied in healthy and unhealthy individuals.
Investigators
Niku Oksala
Prof, MD, PhD, DSc
Tampere University
Eligibility Criteria
Inclusion Criteria
- •for CLTI patients age \>50
- •for age control group age \>50 and not diagnosed with cardiovascular diseases. 0.9 \< ABI \< 1.3
- •for healthy group 18 \<= age \<= 50 and no history of cardiovascular disease
- •volunteering for study
Exclusion Criteria
- •inability to give informed consent
Outcomes
Primary Outcomes
Perfusion in lower limb angiosomes assessed by thermal imaging
Time Frame: 45 minutes during the procedure starting from the first measurement and ending after the last measurement
Thermal imaging will be used to assess the perfusion in the lower limbs. The lower limb can be divided into six angiosomes, which can then be used to assess thermal patterns. Healthy and unhealthy feet will present with different thermal patterns and other changes in thermographs.
Oxygenation in lower limb angiosomes assessed by hyperspectral imaging.
Time Frame: 45 minutes during the procedure starting from the first measurement and ending after the last measurement
Hyperspectral imaging can be used in the assessment of oxygenation in the lower limb angiosomes. Based on hyperspectral imaging, oxygenation maps can be generated and then analyzed. Differences between the oxygenation maps of healthy and unhealthy patients will be established.