Role of topical oxytocin in improving vaginal atrophy in postmenopausal women: A randomized controlled trial
Not Applicable
- Conditions
- post-menopausal vaginal atrophy
- Registration Number
- PACTR201704002167269
- Lead Sponsor
- Air-Force specialized Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 140
Inclusion Criteria
¿ Healthy postmenopausal women (at least two years after menopause) who were suffering from symptoms of vaginal atrophy (such as vaginal dryness, pain, itching, discomfort and bleeding during intercourse).
¿ Had not used any estrogen or other hormonal treatments (systemic or topical) during a four-week period prior to the trial.
Exclusion Criteria
¿ Any chronic illnesses.
¿ Allergy to oxytocin or cellulose.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ¿Visual and colposcopic changes in vaginal mucosa ;¿Histopathological evaluation of punch biopsy of the vaginal mucosa ;Symptoms (Dyspareunia & soreness)
- Secondary Outcome Measures
Name Time Method ¿Serum level of estradiol