Endoarterial Treatment in Combination With Percutaneous Thermoablation for Medium-sized and Oligonodular Hepatocellular Carcinomas

Completed

• Conditions: Carcinoma, Hepatocellular

• Registration Number: NCT04172194
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

Background: The association of transcatheter arterial chemotherapy infusion (TAC) with percutaneous ablation (PT) has been introduced as a method to increase the ablative zone. The aim of this study was to evaluate the efficacy of PT and TAC performed in a single session for HCCs between 30 and 50 mm or oligonodular up to 30 mm.

Methods: Thirty patients with a histologically proven HCC, uninodular between 30 and 50 mm or oligonodular (n≤3) up to 30 mm, treatment-naïve and non-metastatic, received combination treatment ("PT+TAC group"). A "control" group consisted of 34 patients with uninodular HCC up to 30 mm without any poor prognostic criteria treated with PT alone ("PT group").

Detailed Description

Not available

Study Timeline

• Study Start: 2009-01-01
• Primary Completion: 2014-12-31
• Study Completion: 2014-12-31
• Status Verified: 2019-11
• Study First Submitted: 2019-11-19
• Study First Submitted QC: 2019-11-20
• Last Update Submitted: 2019-11-20
• Study First Posted: 2019-11-21
• Last Update Posted: 2019-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• hepatocellular carcinoma pouved by pathology,

Exclusion Criteria

• metastases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
overall survival	30 minutes	death

Secondary Outcome Measures

Name	Time	Method
relapse free survival	30 minutes	relapse
tolerance	30 minutes	apparition of complication define by CTCAE v5.0

Trial Locations

Locations (1)

Nice Hospital; 🇫🇷 Nice, France