Resuscitation Outcomes in the Netherlands Flashmob Questionnaire

Completed

• Conditions: DNR-orders; Cardiopulmonary Arrest
• Interventions: Behavioral: Questionnaire

• Registration Number: NCT03807206
• Lead Sponsor: Erasmus Medical Center

Brief Summary

The aim of this study is to gain insight in patients' experiences regarding do not resuscitate conversations and decisions. A multicentre flash mob investigation will be conducted in which data will be obtained over the course of two weeks using electronic questionnaires that patients will fill out. General demographic data and a brief quality of life assessment (EQ-5D) will be collected. Whether a DNR converstation has taken place will be noted, along with patients' experiences with this conversation. Lastly the patient will be asked about his/her expectations of survival after cardiopulmonary resuscitation.

Detailed Description

Rationale: In-hospital cardiac arrest, associated with a survival to discharge of 15.0%, results in a good neurologic discharge in 9.1% - 30.0% of patients. Therefore it is recommended to engage in advanced care planning with patients, to discuss do-not-resuscitate (DNR) directives. In current knowledge, there are no published data about the prevalence of these DNR orders and associated factors in hospitalized patients in the Netherlands. Also, the conversation about DNR are sometimes perceived as awkward or untimely by patients.

Objective: The primary goal is to estimate prevalence DNR order in Dutch hospitals. A secondary goal is to assess what geographical, patient and disease factors are associated with DNR status. Furthermore patient experience in the conversation leading to DNR-orders is of interest.

Study design: A cross-sectional point prevalence study, in 10 participating hospitals of the ROUTiNE project.

Study population: Patients who plan to be admitted for more than 24 hours to the participating hospitals, aged 18 or older, who are responsive and conscious.

Main study parameters/endpoints: The prevalence of DNR orders, expressed as number per 1000 beds.

Nature and extent of the burden and risks associated with participation, benefit and group relatedness: There is no risk. Only one ten-minute interview per participant. Therefore the benefit of this study (as described in the objectives) outweigh the potential risks.

Study Timeline

• Study Start: 2019-01-01
• Study First Submitted: 2019-01-07
• Study First Submitted QC: 2019-01-15
• Study First Posted: 2019-01-16
• Primary Completion: 2019-02-07
• Study Completion: 2019-02-07
• Status Verified: 2019-07
• Last Update Submitted: 2019-07-14
• Last Update Posted: 2019-07-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1136

Inclusion Criteria

• All patients admitted to the participating hospitals with a planned admission >24 hours at the moment this study takes place.

Exclusion Criteria

• • Refusal to participate

  • <18 years of age

  • Admitted in outpatient clinic and day treatment centres (e.g. haemodialysis)

  • Admitted <24 hours, as defined by not sleeping overnight in hospital

  • No reliable proxy in the following situations:

    • Unable to answer questions (e.g. unconscious, cognitively impaired, delirious)
    • Language barrier (with no interpreter or family member)

  • The following hospital departments are excluded:

    • Intensive care unit
    • Coronary/acute cardiac care unit
    • Obstetrics
    • Paediatrics
    • Stroke unit
    • Dialysis (outpatient dialysis)
    • Day-care wards/short-stay (i.e. <1 day)
    • Palliative care

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Flashmob 2019	Questionnaire	Patients from the following hospitals will receive a questionnaire/structured intereview: Erasmus MC, Franciscus Gasthuis \& Vlietland, Ikazia, Haaglanden Medisch Centrum, Albert Schweitzer ziekenhuis, Jeroen Bosch ziekenhuis, Rijnstate ziekenhuis, Amphia ziekenhuis, Tergooi klinieken, Medisch Spectrum Twente, Reinier de Graaf gasthuis. Pending: Maasstad ziekenhuis

Primary Outcome Measures

Name	Time	Method
Prevalence of DNR-orders	1 day	Percentage of DNR-orders in the total cohort as noted in the electronic patient file

Secondary Outcome Measures

Name	Time	Method
DNR-order discussion experience	1 day	Patient experience with the DNR-order discussion; was it timely, was the explanation clear?
DNR-order discrepancy	1 day	DNR-order reported by the patient, compared to DNR-order from the electronic patient file
DNR-order discussion prevalence	1 day	Number of patients who have had a DNR discussion with their physician
Quality of life	1 day	EQ-5D (Euroqol): EQ-5D-5L is a standardized, participant-rated instrument for use as a measure of health outcomes. The EQ 5D-5L includes 2 components: the EQ-5D-5L descriptive system and the visual analogue scale (VAS). The EQ-5D-5L descriptive system provides a profile of the participant's health state in 5 dimensions (mobility, self-care, usual activities, pain/discomfort, and anxiety/depression). For each dimension, the participant is instructed to choose one of 5 levels that best describes their health on that day: "no problem" (1), "slight" (2), "moderate" (3), "severe" (4), or "unable/extreme" (5). The VAS is the participant's rating of their health on a scale of 0 "worst health you can imagine" to 100 "best health you can imagine".

Trial Locations

Locations (12)

Rijnstate; 🇳🇱 Arnhem, Netherlands

Haaglanden Medisch Centrum; 🇳🇱 Den Haag, Netherlands

Amphia; 🇳🇱 Breda, Netherlands

Reinier de Graaf gasthuis; 🇳🇱 Delft, Netherlands

Jeroen Bosch ziekenhuis; 🇳🇱 Den Bosch, Netherlands

Albert Schweitzer ziekenhuis; 🇳🇱 Dordrecht, Netherlands

Medisch Spectrum Twente; 🇳🇱 Enschede, Netherlands

Tergooi ziekenhuizen; 🇳🇱 Hilversum, Netherlands

Ikazia; 🇳🇱 Rotterdam, Netherlands

Erasmus MC; 🇳🇱 Rotterdam, Netherlands

Franciscus Gasthuis & Vlietland; 🇳🇱 Rotterdam, Netherlands

Maasstad; 🇳🇱 Rotterdam, Netherlands