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Treatment of Peri-Implant Mucositis With Standard of Care and Bioptron Hyperlight Therapy

Not Applicable
Completed
Conditions
Dental Implant Failed
Mucositis Oral
Interventions
Device: Photobiomodulation with Bioptron Hyperlight Therapy
Registration Number
NCT05307445
Lead Sponsor
University of Roma La Sapienza
Brief Summary

Objectives:

The aim of this study was to evaluate in a cohort of patients with peri-implant mucositis: (a) the efficacy of professional mechanical debridement therapy assisted using Bioptron Hyperlight Therapy on the reduction of periodontal indexes (b) the reduction of total oxidative salivary stress.

Material and Methods Forty subjects with a diagnosis of peri-implant mucositis were enrolled in this study and randomly assigned to the study group (mechanical debridement therapy assisted using Bioptron Hyperlight Therapy) or control group (mechanical debridement therapy alone). The study duration was 6 months. Data on plaque index (PI), bleeding on probing (BoP), probing pocket depth (PPD) and pain relief on Visual Analogue Scale (VAS) were recorded at T0, T1 (14 days), T2 (1 month) and T3 (6 months). Group differences were assessed using Student's t-test and Pearson's Chi-squared test of homogeneity

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Male or female, 30-60 years old.
  • With diagnosis of peri-implant mucositis.
  • Plaque index (PI) ≥ 40%.
  • Al least one implant site with PPD≥4 mm, BOP+ and suppuration.
  • No uncontrolled diabetes, cardiovascular diseases, bone metabolism disorders, no autoimmune diseases (lichen planus, pemphigoid, pemphigus and systemic lupus erythematosus).
  • No pharmacological therapies, no chemo-radiotherapies.
  • No smoking (>10 cigarettes/day), alcohol and/or drug consumption.
  • No pregnancy or breastfeeding.
  • No allergy.
Exclusion Criteria

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
peri-implant mucositis treated with photobiomodulation in addition to standard treatmentPhotobiomodulation with Bioptron Hyperlight Therapypatients with peri-implant mucositis are treated with photobiomodulation in addition to standard treatment
peri-implant mucositis treated with standard of care-professional mechanical debridementPhotobiomodulation with Bioptron Hyperlight Therapypatients with peri-implant mucositis are treated with standard of care, i.e. professional mechanical debridement
Primary Outcome Measures
NameTimeMethod
Periodontal chart-Bleeding on probing (BOP)Patients were assessed at 24 weeks (T3)

Bleeding on probing (BOP). Bleeding on probing (BOP) is a parameter to measure soft tissue inflammation. It is measured with the use of a dental probe. The grading is :

* 0: normal colour of gingiva, no inflammation, no bleeding;

* 1: slight inflammation; no bleeding;

* 2: moderate inflammation; presence of bleeding on probing;

* 3: severe inflammation; tendency to spontaneus bleeding.

Periodontal chart-Probing pocket depth (PPD)Patients were assessed at 24 weeks (T3)

Probing pocket depth (PPD). PPD is a periodontal index. It is used to measure the depth of the tissue surrounding the dental implant; with notches measured in millimeters. The probe is placed in between the dental implant and gums and measures the depth of what is called the periodontal pocket- the space between the dental implant and the surrounding gums and bone.

Periodontal chart- Plaque index (PI)Patients were assessed at 24 weeks (T3)

Plaque index (PI). Plaque index is used to evaluate the level and rate of plaque formation on dental implant surfaces. The grading is :

* 0: no visible plaque;

* 1: thin plaque layer detectable by scraping;

* 2: moderate plaque layer; visible to the naked eye;

* 3: abundant plaque layer.

Secondary Outcome Measures
NameTimeMethod
Pain reliefPatients were assessed at 24 weeks (T3)

Pain relief assessed with the Numerical Rating Scale-11 (NRS-11)

Trial Locations

Locations (1)

Roberto Felice Grassi

🇮🇹

Bari, Italy

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