ESPB Versus INB With PCIA in Video-assisted Thoracic Surgery

Not Applicable

Completed

• Conditions: Lung Diseases
• Interventions: Drug: Intercostal Nerve Block with PCIA; Drug: Erector Spinae Plane Block (ESPB)

• Registration Number: NCT03682354
• Lead Sponsor: Peking University Third Hospital

Brief Summary

A randomized prospective trial to test the non-inferiority of erector spinae plane block (ESPB) in comparison with intercostal nerve block combined with patient-controlled intravenous analgesia in Thoracoscopic lung surgery

Detailed Description

For patients undergoing thoracic surgery, postoperative pain greatly limited their recovery.Multimodal analgesia have shown good efficacy but without reaching full pain relief.

The primary goal of this study is to observe the effect of ultrasound-guided erector spinae plane block in comparison with intercostal nerve block combined with patient-controlled intravenous analgesia in video assisted thoracic lung surgery.

Study Timeline

• Study First Submitted: 2018-08-26
• Study First Submitted QC: 2018-09-20
• Study First Posted: 2018-09-24
• Study Start: 2018-09-27
• Status Verified: 2019-03
• Primary Completion: 2019-03-15
• Study Completion: 2019-03-15
• Last Update Submitted: 2019-03-26
• Last Update Posted: 2019-03-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Patients to receive video assisted thoracoscopic lobectomy or bullectomy .

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Exclusion Criteria

• 1. Patient refusal 2. Heavy skin eruption and infection at site of injection. 3. Coagulopathy. 4. Allergy to local anesthetics. 5. Taking analgesics.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intercostal Nerve Block with PCIA	Intercostal Nerve Block with PCIA	Intercostal Nerve Block with patient-controlled intravenous analgesia
Erector Spinae Plane Block (ESPB)	Erector Spinae Plane Block (ESPB)	Continuous Erector Spinae Plane Block

Primary Outcome Measures

Name	Time	Method
Pain score (NRS)	4 hours from the end of procedure	Numeric Rating Scale is an 11-point scale used by doctors to evaluate patients' pain, where 0 is no pain and 10 the worst imaginable pain. For postoperative patients, an higher score shows inadequate analgesia and worse outcome.

Secondary Outcome Measures

Name	Time	Method
Pain score (NRS)	8, 24,48 hours from the end of procedure	Numeric Rating Scale is an 11-point scale used by doctors to evaluate patients' pain, where 0 is no pain and 10 the worst imaginable pain. For postoperative patients, an higher score shows inadequate analgesia and worse outcome.
Incidence of side effects and complication during study	During operation,4, 8, 24,48 hours from the end of procedure	Side effects and complication
Analgesics consumption	During operation,4, 8, 24,48 hours from the end of procedure	Analgesics include opioids and nonsteroidal anti-inflammatory drugs

Trial Locations

Locations (1)

Peking University Third Hospital; 🇨🇳 Beijing, China