Well being of patients with thyrotoxicosis after radioactive iodine treatment using block and replace compared to titrated regime

Not Applicable

Completed

• Conditions: utritional, Metabolic, Endocrine: Hyperthyroidism; Nutritional, Metabolic, Endocrine; Thyrotoxicosis [Hyperthyroidism]

• Registration Number: ISRCTN27681212
• Lead Sponsor: Record Provided by the NHSTCT Register - 2006 Update - Department of Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-09-29
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Toxic nodular thyroid disease (toxic multinodular goitre or toxic nodule)
2. Garves' thyrotoxicosis with patients' preference to have RAI
3. Recurrent Graves' thyrotoxicosis
4. Age between 18 and 80 years.

According to the current local practice, patients needing radioactive iodine treatment will be seen by our Endocrine Specialist Nurses. These patients will be assessed for their eligibility for this study. If the patients are eligible, they will be given the information sheet about the study. If they are happy to take part, before the radioactive iodine treatment, written consent will be obtained and patients will be randomised at that stage.

Exclusion Criteria

1. Pregnant or lactating women
2. Patients allergic to antithyroid drugs or iodine
3. Active thyroid eye disease
4. Known alcohol or drug abuse
5. Significant psychiatric disturbances

Study & Design

• Study Type: Interventional
• Study Design: Not specified