Exploratory Clinical Study on the Effectiveness of Glycyrrhizin in Early Vascular Lesions of Systemic Sclerosis

Phase 1

Recruiting

• Conditions: Systemic Sclerosis

• Registration Number: JPRN-UMIN000032238
• Lead Sponsor: The University of Tokyo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-04-13
• Last Update Posted: 20 November 2023
• Study Completion: 2026-05-21

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients with aldosteronism, myopathy or hypokalemia 2)Patients with cirrhosis with more than 70 microgram/dL serum ammonia concentration 3)Patients less than 3 months after the final administration of the other test drugs or investigational drugs 4)Patients with more than 10 MRSS (modified Rodnan total skin thickness score) 5)Patients with not satisfy% VC 80% and % DLCO 70% in respiratory function test 6)Patients with eGFR less than 45 mL / min / 1.73 m2 7)Patients with more than RVSP>40mmHg pulmonary hypertension 8)Patients with complications of systemic lupus erythematosus or dermatomyositis 9)Patients with a history of malignant tumors 10)Patients with a history of severe hypersensitivity or anaphylactic reaction to the components of test drug 11)patient judged by doctor as inappropriate

Study & Design

• Study Type: Interventional
• Study Design: Not specified