Exploratory Clinical Study on the Effectiveness of Glycyrrhizin in Early Vascular Lesions of Systemic Sclerosis - The Effectiveness of Glycyrrhizin in Systemic Sclerosis

The University of Tokyo0 sites20 target enrollmentApril 13, 2018

Overview

No summary available.

Registry

who.int

Start Date

April 13, 2018

End Date

May 21, 2026

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

•1\)Patients with aldosteronism, myopathy or hypokalemia 2\)Patients with cirrhosis with more than 70 microgram/dL serum ammonia concentration 3\)Patients less than 3 months after the final administration of the other test drugs or investigational drugs 4\)Patients with more than 10 MRSS (modified Rodnan total skin thickness score) 5\)Patients with not satisfy% VC 80% and % DLCO 70% in respiratory function test 6\)Patients with eGFR less than 45 mL / min / 1\.73 m2 7\)Patients with more than RVSP\>40mmHg pulmonary hypertension 8\)Patients with complications of systemic lupus erythematosus or dermatomyositis 9\)Patients with a history of malignant tumors 10\)Patients with a history of severe hypersensitivity or anaphylactic reaction to the components of test drug 11\)patient judged by doctor as inappropriate