Do-It study Depression & Occupation: Intervention Trial

Conditions: major depression

Registration Number: NL-OMON30302

Lead Sponsor: Academisch Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 160

Inclusion Criteria

- age: 18-65 years
- diagnosis: depressive and/or dysthymic disorder (DSM IV) ;- labour effect: absenteeism or partial absenteeism (minimum of 25% absenteeism)
- duration absenteeism more than 8 weeks OR duration DSMIV diagnosis depression more than 3 months
- reintegration: possibility to return to own or new job
- relation between depressive disorder and work:
o work is one of the determinants of depressive disorder and contributes substantially (>25%) or
o depressive symptoms reduces productivity or hinders the return to work
- occupational therapy is an acceptable intervention for the patient

Exclusion Criteria

- bipolar disorder
- psychotic disorder or depression with psychotic characteristics
- severe alcohol or drug misuse/alcohol or drug dependence
- severe physical problems that make participation to the study impossible
- inpatient treatment at the clinic is indicated for patient
- current participation in depression or occupational therapy cannot be discontinued
- current participation in research study that enables participation in the DO IT study

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary parameters:<br /><br>- work absenteism (work loss days, work cut back days)<br /><br>- work productivity<br /><br>- work functioning</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary parameters:<br /><br>- psychopathology: depressive symptoms<br /><br>- health related quality of life<br /><br>- costs<br /><br>- neurocognitive functies (concentration, memory deficits)</p><br>