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Clinical Trials/NCT02325167
NCT02325167
Completed
Not Applicable

Short-term Existential Behavioural Therapy for Informal Caregivers of Palliative Patients: a Randomised Controlled Trial

Ludwig-Maximilians - University of Munich1 site in 1 country130 target enrollmentStarted: January 2015Last updated:
ConditionsDepression

Overview

Phase
Not Applicable
Status
Completed
Enrollment
130
Locations
1
Primary Endpoint
Patient Health Questionnaire-9 (PHQ-9)

Overview

Brief Summary

The purpose of the study is to test the effectiveness of a short-term manualised individual psychotherapy, called Existential Behavioural Therapy (EBT), to prevent depression in informal caregivers of palliative patients.

Detailed Description

The investigators have developed and pilot-tested a short-term manualised individual psychotherapy, called Existential Behavioural Therapy (EBT), to reduce psychological distress in informal caregivers of palliative patients. The investigators propose to conduct a two-arm randomised controlled trial (RCT) to test the effectiveness of EBT against usual care for the reduction of distress and the promotion of quality of life.

Two one-to-one manualised psychotherapeutic sessions will be compared to a treatment-as-usual control group.Treatment-as-usual includes two supportive sessions.

The design will be an unblinded RCT consisting of two conditions (EBT and Treatment-as-usual), with assessment at pre- and post-treatment and follow-ups at four weeks and six months. The trial will take place in the Clinic of Palliative Care, University of Munich (Klinik und Poliklinik für Palliativmedizin der LMU München).

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
None

Eligibility Criteria

Ages
21 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • ≥ 21 years of age
  • informal caregivers of palliative patients at last stage of life and during bereavement;
  • fluent German language skills

Exclusion Criteria

  • psychiatric conditions such as schizophrenic disorder, psychotic disorder etc.;
  • pronounced cognitive impairment e.g. delirium, dementia

Outcomes

Primary Outcomes

Patient Health Questionnaire-9 (PHQ-9)

Time Frame: Baseline; Post-treatment; 4 weeks follow-up; 6 months follow-up

A reliable and valid 9-item measure of depression

Secondary Outcomes

  • Positive and Negative Affect Scale (PANAS; Watson et al., 1988)(Baseline; Post-treatment; 4 weeks follow-up; 6 months follow-up)
  • Satisfaction with Life Scale (SWLS; Diener et al., 1985)(Baseline; Post-treatment; 4 weeks follow-up; 6 months follow-up)
  • World Health Organisation Quality-of-Life Scale (WHOQOL-BREF; Angermeyer et al., 2000)(Baseline; Post-treatment; 4 weeks follow-up; 6 months follow-up)
  • Numeric rating scale for mental stress and quality of life (NRS, range 0-10)(Baseline; Post-treatment; 4 weeks follow-up; 6 months follow-up)
  • Generalised Anxiety Disorders-7 (GAD-7; Spitzer et al., 2006)(Baseline; Post-treatment; 4 weeks follow-up; 6 months follow-up)
  • Fragebogen zur Inanspruchnahme medizinischer und nicht-medizinischer Versorgungsleistungen im Alter (FIMA; Seidl et al., 2014)(Baseline; 6 months follow-up)
  • German version of the NCCN distress-thermometer (Mehnert et al., 2005)(Baseline; Post-treatment; 4 weeks follow-up; 6 months follow-up)
  • General Health Questionnaire (GHQ-12, Goldberg et al., 1972)(Baseline; Post-treatment; 4 weeks follow-up; 6 months follow-up)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Martin Fegg

PD Dr. Martin Fegg

Ludwig-Maximilians - University of Munich

Study Sites (1)

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