NCT00673842已完成3 期
Risk Estimation Following Infarction Noninvasive Evaluation - ICD Efficacy
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 700
- 试验地点
- 139
- 主要终点
- Mortality
研究概览
简要总结
This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack, have abnormal test results from a 24 hour heart monitor, and who have low normal heart function.
详细描述
The REFINE ICD trial will assess whether prophylactic ICD therapy, guided by non-invasive risk assessment tools, reduces mortality in MI survivors with better-preserved LV function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Mortality
时间窗: Minimum of 18 months of follow-up (average follow-up of 5 years).
次要结局
- Appropriate ICD therapies(Average follow-up 5 years.)
- Arrhythmic syncope(Average follow-up 5 years.)
- Quality of life(Average follow-up 5 years.)
- Cardiac death(Average follow-up 5 years.)
- Arrhythmic death(Average follow-up 5 years.)
- Inappropriate ICD therapies(Five years (average))
研究者
Dr. Derek Exner
Professor and Canada Research Chair in Cardiovascular Clinical Trials
University of Calgary
研究点 (139)
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