Phase II study of Neoadjuvant Letrozole for Postmenopausal Women with Endocrine-responsive and Anthracycline non-responsive Breast Cancer (JBCRG-06)
Phase 2
- Conditions
- Postmenopausal, hormone-receptor positive and primary breast cancer
- Registration Number
- JPRN-UMIN000001325
- Lead Sponsor
- Japan Breast Cancer Research Group (JBCRG)
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 0
Inclusion Criteria
Not provided
Exclusion Criteria
1. Unmanageable serious complications 2. HCV 3. Unmanageable diabetes 4. Suspicious infection with fever 5. Active double cancer 6. Inflammatory breast cancer 7. Bilateral breast cancer 8. 10. History of drug-hypersensitivity 9. Receiving continuous systematic steroids, estrogen and Raloxifene 10. Mental disease 11. Patient judged inappropriate for this study by the physicians
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response rate
- Secondary Outcome Measures
Name Time Method Pathological CR rate, Breast Conserving Surgery rate, Safety, Disease- free survival and Overall survival