Effects and Safety of Intranasal Phototherapy for Allergic Rhinitis

Recruitment & Eligibility

Status: Active, not recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

Presence of two or more symptoms of allergic rhinitis(nasal congestion, rhinorrhea, nasal itching and sneezing) and Positive reaction to an allergen in multiple allergen simultaneous test

Exclusion Criteria

1) Patients who take any medication as follows or who can’t stop taking medication which is unsuitable for this clinical trail.(But they can be enrolled in this trial after the minimum Wash-out period as suggested, before Visit2.)
? anti-histamine/H1 blockers within the last 7days
? corticosteroids(intranasal) within the last 14days
? corticosteroids(systemic) within the last 30days
? anti-cholinergic drug within the last 7days
? anti-leukotriene drug within the last 4weeks
? decongestants within the last 3days
? tricyclic antidepressants, phenothiazines within the last 14days
? non-steroidal analgesics within the last 14days
? Others (inappropriate medications)
2) Korean Medicine treatment(herbal medicine, acupuncture, moxibustion, cupping, etc) to treat allergic rhinitis within the past 14days
3) Laser therapy to treat allergic rhinitis within the past 14days
4) Malignant neoplasm, anemia, active pulmonary tuberculosis, infection or other severe systemic disease
5) Anatomical obstruction or deformities of the nasal cavity or nasal surgery within the past 6months
6) Past history of active respiratory disease like asthma
7) Hypertension or diabetes
8) Immunotherapy or systemic corticosteroids therapy within the past 2 years
9) hypersensitivity reaction to phototherapy or taking related drugs
10) scar on the irradiation spot
11) Pregnancy, planning a pregnancy or breast-feeding
12) Participation in other clinical trials within the past 1 month
13) Difficulties in enrolling this trial or receiving treatmen
14) Ineligibility for participation as judged by the investigator

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TNSS(Total Nasal Symptom Score)

Secondary Outcome Measures

Name	Time	Method
RQLQ(Rhinoconjunctivitis Quality of Life Questionnaire);Serum ImmunoglobulinE, Eosinophil count;Nasal endoscopy;Adverse event

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