NCT05160610招募中不适用
Improving Thrombolysis Implementation Based on Electronic Monitoring in Acute Ischemic Stroke (ITEM): a Cluster Randomized Controlled Trial
Second Affiliated Hospital, School of Medicine, Zhejiang University1 个研究点 分布在 1 个国家目标入组 2,720 人开始时间: 2022年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2,720
- 试验地点
- 1
- 主要终点
- Thrombolysis rate within 4.5 hours
研究概览
简要总结
A cluster randomized controlled trial will be conducted. Hospitals in Zhejiang Province, China, will be randomized into two arms (1:1): an intervention arm and a control arm.
Hospitals in the intervention arm will receive a multilevel intervention based on the AACTT theory, whereas hospitals in the control arm will receive no intervention and maintain routine care. All the hospitals will receive electronic monitoring. Hospitals with no stroke center or with <20 cases received thrombolysis per year will be excluded from the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients presented with clinical signs of acute ischemic stroke within 4.5 hours of stroke onset
- •Patient's age is >18 years
排除标准
- •Contraindication for intravenous thrombolysis
结局指标
主要结局
Thrombolysis rate within 4.5 hours
时间窗: Up to 4.5 hours
The proportion of acute ischemic stroke patients within 4.5 hours of onset
次要结局
- Excellent neurological outcomes(At 90 days)
- modified Rankin Scale score(At 90 days)
- Favorable neurological outcomes(At 90 days)
- All-cause death rate(At 90 days)
- Symptomatic intracranial hemorrhage(At 7 days)
- Thrombolysis rate within 3 hours(Up to 3 hours)
- Hemorrhagic transformation(At 7 days)
- Door-to-image time(Up to 4.5 hours)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Improving In-hospital Stroke Service Utilisation in ChinaThrombolytic TherapyAcute StrokeDoor to Treatment TimeQuality ImprovementNCT03317639Second Affiliated Hospital, School of Medicine, Zhejiang University1,634
进行中（未招募）
不适用
A Tool Kit to Improve Vaccine Confidence in the PhilippinesMeaslesPolioVaccination HesitancyNCT06218368University of Toronto5,400
已完成
不适用
A National School-based Health Lifestyles Interventions Among Chinese Children and Adolescents Against ObesityPediatric ObesityNCT02343588Sun Yat-sen University70,000
已完成
2 期
A Pilot Study of an RCT to Improve Infection Management in Advanced DementiaDementiaNCT01966523Hebrew SeniorLife62
招募中
4 期
Antithrombotic Strategy Based on Clinical Events and 4D-CT for Patients After TAVRTranscatheter Aortic Valve ReplacementAntithrombotic TherapyBioprosthetic Valve ThrombosisNCT05375474China National Center for Cardiovascular Diseases650