The Outcome of Three Weeks Rehabilitation in Patients With a Total Hip or Knee Replacement Experiencing Persistent Physical Impairments

Recruiting

• Conditions: Hip Osteoarthritis; Knee Osteoarthristis

• Registration Number: NCT07105657
• Lead Sponsor: Horsens Hospital

Brief Summary

Patients with total hip or knee replacement experiencing persistant problems are offered 3 weeks of intensive rehabilitation.

Detailed Description

Outcomes before, at the end of treatment and at 6 months follow up will be investigated. Data will be handled separately for the two groups of patients: 42 with a total hip replacement and 42 with a total knee replacement. Specific and generic outcomes will be collected.

Study Timeline

• Study First Submitted: 2025-07-30
• Study First Submitted QC: 2025-07-30
• Status Verified: 2025-08
• Study First Posted: 2025-08-06
• Study Start: 2025-08-25
• Last Update Submitted: 2025-08-25
• Last Update Posted: 2025-08-26
• Primary Completion: 2027-12-31
• Study Completion: 2027-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 84

Inclusion Criteria

- Patients with a total hip or knee replacement admitted for intensive rehabilitation

Exclusion Criteria

• Patients unable to understand Danish
• Unable to participate in physical tests
• Unable to understand questionaires
• Unable to participate i 6 months follow up

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HOOS/KOOS pain (0-100 score)	Change from 3 weeks to 7 months	Hip or knee related pain
HOOS/KOOS ADL (0-100 score)	Change from 3 weeks to 7 months	Hip or knee related activities of daily living
HOOS/KOOS quality of life (0-100 score)	Change from 3 weeks to 7 months	Hip or knee related quality of life
Sit-to-stand test	Change from 3 weeks to 7 months	Number of completed sit to stands in 30 seconds

Secondary Outcome Measures

Name	Time	Method
Patient acceptable symptom state (yes/no)	7 months follow up	Patients are asked with a single question if their current symptom state is acceptable
Pain catastrophising scale (0-52 score)	7 months	Current level of pain catastrophising with 0 being the best
The 5-level EQ-5D version (EQ-5D-5L) (0-5 scale)	Change from 3 weeks to 7 mothns	EQ5D5L scores
HOOS/KOOS symptoms (0-100 score)	Change from 3 weeks to 7 months	Hip or knee symptoms
40 meter fast paced walk test	Change from 3 weeks to 7 months	The time a patient uses walking 40 meters fast
Global rating of change (0-11 score)	Change from baseline to 7 months	Likert scale where patients indicate their overall rating of change since the beginning of the intervention
Stair test	Change from 3 weeks to 7 months	The time a patient uses to ascend and decend a staircase
EQ5D VAS (0-100 scale)	Change from 3 weeks to 7 months	EQ5D Vas overall health
HOOS/KOOS sport/rec (0-100 score)	Change from 3 weeks to 7 months	Hip or knee related sport/rec
6 minute walk test	Change from 3 weeks to 7 months	The distance a patient can walk in 6 minutes

Trial Locations

Locations (1)

Horsens Regional Hospital; 🇩🇰 Brædstrup, Denmark