Regulatory Effect of Stachyose on Gut Microbiota and microRNA Expression in Human
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- structure of gut microbiota
研究概览
简要总结
In this study, stachyose was used as an intervention factor. We will evaluate changes in fecal gut microbiota and miRNA expression profiles in subjects under stachyose intervention
详细描述
In the stachyose intervention group, each person in the stachyose intervention group took 5 g of stachyose daily before breakfast, and the administration method was 100 ml of drinking water dissolved and taken orally for two months. Each person in the placebo control group took the same amount of maltodextrin daily. Stool samples of the subjects were collected weekly.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy human
排除标准
- •people who need intake antibiotics，probiotics or its product
结局指标
主要结局
structure of gut microbiota
时间窗: up to 4 weeks
16S rDNA sequencing valuated the gut microbiota composition in human
expression of microRNA
时间窗: up to 4 weeks
small rna sequencing valuated the microRNA expression in human
次要结局
未报告次要终点