Study to evaluate the efficacy, safety and tolerability of pumactant 240mg in the prevention of the formation of peritoneal adhesions following abdominal surgery

Completed

• Conditions: Post operative intraperitoneal adhesions; Surgery

• Registration Number: ISRCTN99599132
• Lead Sponsor: Research and Innovation Service, University of Dundee (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-03-31
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

1. Male and female subjects ( > 18 years old) were recruited into the study if it was thought that at the primary surgical procedure, they required the formation of a temporary stoma
2. Patients undergoing emergency treatment of obstructed /perforated carcinoma of the bowel or colonic diverticulitis by Hartmanns procedure
3. Patients undergoing elective low anterior bowel resection for the treatment of rectal carcinoma requiring formation of a temporary ileostomy

Exclusion Criteria

1. Patients unable to comply with the study requirements, had cognitive impairments, had a history of drug and / or alcohol abuse
2. Patients receiving steroid medication
3. Patients had metastatic disease
4. Patients had American Society of Anesthesiologists (ASA) fitness grade of IV or above
5. Pregnant or lactating females

Study & Design

• Study Type: Interventional
• Study Design: Not specified