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临床试验/NCT01844154
NCT01844154Unknown不适用

Fracture and Fall Prevention in Elderly With Osteoporosis: Long-term Follow up

National Taiwan University Hospital2 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2012年10月最近更新:
适应症

试验速览

阶段
不适用
入组人数
120
试验地点
2
主要终点
Muscle activation during balance recovery

研究概览

简要总结

Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that can cause fracture, injury or mortality. Identifying the factors related to falls occurring within this population is essential for the development of effective regimes for fall prevention. Studies have shown that muscle quality and good posture alignments are critical for balance control in older adults. People are diagnosed with osteoporosis often combining with muscles weakness, and increased spine kyphosis leading vertebral, fractures and poor balance control, even falls. Therefore, improving muscle quality, strengthening weak muscles and correcting postural alignment are essential elements for fracture and fall prevention in older adults with osteoporosis. The long-term objectives of this work are to prevent fracture and fall in older adults with osteoporosis by improving the function of degenerative muscles using exercise training.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
50 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • able to stand and walk for 5 minutes independently
  • having normal or corrected to normal vision
  • having age between > 50 years
  • already have DEXA and X-ray exam with osteopenia (-2.5 < t-score < -1.0) or osteoporosis (t-score <-2.5)

排除标准

  • being pregnant
  • sensory-motor deficits
  • inability of communication
  • lack of access to a telephone
  • t-score <-2.5 combine with existing fracture
  • control age-matched group:
  • Inclusion Criteria:
  • able to stand and walk for 5 minutes independently
  • having normal or corrected to normal vision
  • having age between > 50 years
  • already have DEXA and X-ray exam without osteopenia or osteoporosis (t-score > -1.0)
  • Exclusion Criteria:
  • being pregnant
  • sensory-motor deficits
  • inability of communication
  • lack of access to a telephone
  • t-score <-2.5 combine with existing fracture

结局指标

主要结局

Muscle activation during balance recovery

时间窗: every 3 month, up to 1 year

Data collection will be carried out in 2 sessions in 2 different days within the span of a week. The first day of data collection includes basic information, anthropometric measure, clinical tests, and functional tests. The second day of data collection includes muscle and joint assessment, and biomechanical tests. Each session last approximately 2.5 hours in duration.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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