Fracture and Fall Prevention in Elderly With Osteoporosis

• Conditions: Osteoporosis, Osteopenia

• Registration Number: NCT01844154
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that can cause fracture, injury or mortality. Identifying the factors related to falls occurring within this population is essential for the development of effective regimes for fall prevention. Studies have shown that muscle quality and good posture alignments are critical for balance control in older adults. People are diagnosed with osteoporosis often combining with muscles weakness, and increased spine kyphosis leading vertebral, fractures and poor balance control, even falls. Therefore, improving muscle quality, strengthening weak muscles and correcting postural alignment are essential elements for fracture and fall prevention in older adults with osteoporosis. The long-term objectives of this work are to prevent fracture and fall in older adults with osteoporosis by improving the function of degenerative muscles using exercise training.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-10
• Study First Submitted: 2012-10-05
• Study First Submitted QC: 2013-04-28
• Study First Posted: 2013-05-01
• Status Verified: 2016-03
• Last Update Submitted: 2016-03-02
• Last Update Posted: 2016-03-03
• Primary Completion: 2016-12
• Study Completion: 2016-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• able to stand and walk for 5 minutes independently
• having normal or corrected to normal vision
• having age between > 50 years
• already have DEXA and X-ray exam with osteopenia (-2.5 < t-score < -1.0) or osteoporosis (t-score <-2.5)

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Exclusion Criteria

• being pregnant
• sensory-motor deficits
• inability of communication
• lack of access to a telephone
• t-score <-2.5 combine with existing fracture

control age-matched group:

Inclusion Criteria:

• able to stand and walk for 5 minutes independently
• having normal or corrected to normal vision
• having age between > 50 years
• already have DEXA and X-ray exam without osteopenia or osteoporosis (t-score > -1.0)

Exclusion Criteria:

• being pregnant
• sensory-motor deficits
• inability of communication
• lack of access to a telephone
• t-score <-2.5 combine with existing fracture

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Muscle activation during balance recovery	every 3 month, up to 1 year	Data collection will be carried out in 2 sessions in 2 different days within the span of a week. The first day of data collection includes basic information, anthropometric measure, clinical tests, and functional tests. The second day of data collection includes muscle and joint assessment, and biomechanical tests. Each session last approximately 2.5 hours in duration.

Trial Locations

Locations (2)

National Taiwan University; 🇨🇳 Taipei City, Taiwan

School & Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University; 🇨🇳 Taipei, Taiwan