A comparision of epidural butorphanol and fentanyl as an adjuvant with 0.5%levobupivacaine for postoperative analgesia in patients undergoing vaginal hysterectomy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Duration of analgesia
研究概览
简要总结
This will be a double blinded randomized study conducted to evaluate inj. Butorphenal 2mg and inj. fentanyl 50 mcg as an adjuvant with inj.levobupivacaine 0.5% 15ml epidurally in patients who are between 30 to 70yr old, ASA grade 1 or 2 with excemption of all exclusion criteria mentioned above and undergoing vaginal hysterectomy under epidural analgesia with primary objective of comparing the duration of analgesia. seconadry objectives being onset and duration of sensory block, onset and duration of motor block, cardiovascular effects, side effects . participants will be allocated in to 2 groups each with 40 sample size . Group LB receiving inj.butorphenal group LF receiving inj.fentanyl as an adjuvant with local anaesthetic epidurally in above mentioned dosagey. pre anaesthetic evaluation will be done previous day , necessary premedication will be given , informed written consent will be taken prior to surgery. all emergency drugs and equipments will be kept ready in prior. under all aseptic precautions respective drugs will be given epidurally to respective group of patient. patient will be monitored intraoperative and postoperatively. all the parameters will be recorded at pre described interval and documented. data will be analyses statistically using standard qualitative and quantitative tests. continuous variables will be analyzed using student paired test and chategorical variables will be analyzed using chi-square test. P value of less than 0.05 will be considered significant.
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 30.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- Female
入选标准
- •ASA 1 and 2 female undergoing vaginal hysterectomy.
排除标准
- •ASA >2 comorbidities pregnant patients breastfeeding local infection.
结局指标
主要结局
Duration of analgesia
时间窗: assessment of visual analogue score for pain in postoperative period at immediately after shifting post operative unit,after 1hr,2hr,3hr,4hr, 6hr,8hr,10hr
次要结局
- onset & duration of sensory block(onset duration of motor block)
