In-line Filters on ICU
Completed
- Conditions
- Micropore Filters
- Registration Number
- NCT02281604
- Lead Sponsor
- Johann Wolfgang Goethe University Hospital
- Brief Summary
The purpose of this study is to determine whether the use of 0.2/1.2 microliter in-line filter reduces the incidence of severe vasoplegia comparing to the 5 microliter filter.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 3281
Inclusion Criteria
- all patients
Exclusion Criteria
- Younger than 18 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of severe vasoplegia participants will be followed for the duration of intensive care unit stay, an expected average of 1 week
- Secondary Outcome Measures
Name Time Method Duration of ICU and hospital stay participants will be followed for the duration of intensive care unit/ hospital stay, an expected average of 1 or 4 week (s), respectively Morbidity participants will be followed for the duration of hospital stay, an expected average of 4 weeks Incidence of preoperative myocardial infarction, stroke, pneumonia, sepsis and acute kidney failure according to routine documentation
Inflammation participants will be followed for the duration of intensive care unit stay, an expected average of 1 week Interleukin-6
In-hospital mortality participants will be followed for the duration of hospital stay, an expected average of 4 weeks Organ dysfunction participants will be followed for the duration of intensive care unit stay, an expected average of 1 week Severity of organdysfunction (SOFA-Score), incidence and severity of respiratory failure (Horovitz- Index), incidence and severity of acute kidney failure (RIFLE criteria), incidence and severity of delirium